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SCPA_COXBU
ID   SCPA_COXBU              Reviewed;         266 AA.
AC   Q83CP8;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=CBU_1061;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO90575.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016828; AAO90575.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_820061.2; NC_002971.3.
DR   AlphaFoldDB; Q83CP8; -.
DR   SMR; Q83CP8; -.
DR   STRING; 227377.CBU_1061; -.
DR   EnsemblBacteria; AAO90575; AAO90575; CBU_1061.
DR   GeneID; 1208962; -.
DR   KEGG; cbu:CBU_1061; -.
DR   PATRIC; fig|227377.7.peg.1052; -.
DR   eggNOG; COG1354; Bacteria.
DR   HOGENOM; CLU_038686_0_1_6; -.
DR   OMA; YLVMAAM; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.580; -; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..266
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_0000244642"
SQ   SEQUENCE   266 AA;  30441 MW;  81CB160010E28A0A CRC64;
     MENQEVVNQL AGFEVKVSGQ PLSKLPEDLY IPPDALRVFL EAFEGPLDLL LYLIKKHNID
     ILDIPIAEIT RQYMQFVDLM REMRIELAAE YLVMAAMLAE IKSRLLLPRP VVEEENEQDP
     RAELVRRLQE YERYKKAAYD LDQLPRVGRD TFIADAAVPP MNTAKIHPTA ELPELLNALK
     DVLQRASLYN AHSIAREPLS IRERMSRILS LVDKENFIAF TRLFTVEEGR MGVVVTLIAT
     LELIRQSVIE LVQAEPFALI HIRAKG
 
 
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