ID   SCPA_DESHY              Reviewed;         261 AA.
AC   Q24V65;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=DSY2288;
OS   Desulfitobacterium hafniense (strain Y51).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfitobacterium.
OX   NCBI_TaxID=138119;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y51;
RX   PubMed=16513756; DOI=10.1128/jb.188.6.2262-2274.2006;
RA   Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K.,
RA   Inatomi K., Furukawa K., Inui M., Yukawa H.;
RT   "Complete genome sequence of the dehalorespiring bacterium
RT   Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides
RT   ethenogenes 195.";
RL   J. Bacteriol. 188:2262-2274(2006).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
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DR   EMBL; AP008230; BAE84077.1; -; Genomic_DNA.
DR   RefSeq; WP_005811066.1; NC_007907.1.
DR   AlphaFoldDB; Q24V65; -.
DR   SMR; Q24V65; -.
DR   STRING; 138119.DSY2288; -.
DR   EnsemblBacteria; BAE84077; BAE84077; DSY2288.
DR   KEGG; dsy:DSY2288; -.
DR   eggNOG; COG1354; Bacteria.
DR   HOGENOM; CLU_038686_3_0_9; -.
DR   OMA; YLVMAAM; -.
DR   OrthoDB; 959677at2; -.
DR   Proteomes; UP000001946; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.580; -; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..261
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_1000187561"
SQ   SEQUENCE   261 AA;  29930 MW;  D2A4E79D537C66AB CRC64;
     MSNGSSVSHS ANTAPYVELP AFQGPMDLLL HLIQQEKVDI YDIPIARITD QFIQVVRQME
     DLDMEVTTEF LVLAAQLLQI KSRYLLPKPV KDVTVEEEGD PRQELVERLL AYRAFKQAAE
     TLGEIQISSG QRYFREVDVD GLRSQFTPAD PLAGIHFEAL WHAFQRIIER AEQGEEIRTV
     EPDEIPIEVM VNDVLRRVIL HPRGLRFSQL IRGTKRMEII VSFLALLELL KSGKVHCEQS
     SQNEEIFVFP TEKAWEFTEG E