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SCPA_LACLA
ID   SCPA_LACLA              Reviewed;         242 AA.
AC   Q9CG33;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=LL1277;
GN   ORFNames=L108989;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
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DR   EMBL; AE005176; AAK05375.1; -; Genomic_DNA.
DR   PIR; E86784; E86784.
DR   RefSeq; NP_267433.1; NC_002662.1.
DR   RefSeq; WP_003130199.1; NC_002662.1.
DR   AlphaFoldDB; Q9CG33; -.
DR   SMR; Q9CG33; -.
DR   STRING; 272623.L108989; -.
DR   PaxDb; Q9CG33; -.
DR   DNASU; 1114926; -.
DR   EnsemblBacteria; AAK05375; AAK05375; L108989.
DR   KEGG; lla:L108989; -.
DR   PATRIC; fig|272623.7.peg.1380; -.
DR   eggNOG; COG1354; Bacteria.
DR   HOGENOM; CLU_038686_3_3_9; -.
DR   OMA; YLVMAAM; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.580; -; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..242
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_0000211086"
SQ   SEQUENCE   242 AA;  28428 MW;  B5E624D74BB355B7 CRC64;
     MIKEINIKIK NFEGPLDLLL HLVSQYEMDI FEVPLVPVIE QYLIYIQTMK ELELEVAGEY
     MLMASQLMLI KSRRLLPTVT ETFIEDTEQL EYDLLAQIDE YRKYKMLSQD LDELHQERSH
     FYSKAKTEII TDETVLLQDK SALDLFLAFT KILELQRQHF QDENTKIAAE KFTIADKILE
     LSTRFTEQKI CKFSDLFSSS TNKDELVTTF MALLELIKNQ QISFSQGELF GEIILERKET
     SE
 
 
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