ID   SCPA_LIGS1              Reviewed;         261 AA.
AC   Q1WTK0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=LSL_0940;
OS   Ligilactobacillus salivarius (strain UCC118) (Lactobacillus salivarius).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=362948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCC118;
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K.,
RA   Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
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DR   EMBL; CP000233; ABD99750.1; -; Genomic_DNA.
DR   RefSeq; WP_011476059.1; NC_007929.1.
DR   RefSeq; YP_535833.1; NC_007929.1.
DR   AlphaFoldDB; Q1WTK0; -.
DR   SMR; Q1WTK0; -.
DR   STRING; 362948.LSL_0940; -.
DR   PRIDE; Q1WTK0; -.
DR   EnsemblBacteria; ABD99750; ABD99750; LSL_0940.
DR   GeneID; 57059370; -.
DR   KEGG; lsl:LSL_0940; -.
DR   PATRIC; fig|362948.14.peg.1015; -.
DR   HOGENOM; CLU_038686_3_1_9; -.
DR   OMA; YLVMAAM; -.
DR   Proteomes; UP000006559; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..261
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_1000069974"
SQ   SEQUENCE   261 AA;  30378 MW;  725F1F0AE90404E4 CRC64;
     MAQENKQNSR TAEHLTFKLD QFEGPLDLLL HLIKQNEMDI YDIQVAEITS QYIDYLHQMQ
     DLRLDIAGEY LVIAATLLNI KSKMLLPVEQ EQQVEEDYVD PREDLVQQLV SHQLYQEVAA
     KFHVMEKQRM ELFSREQAVN EDVTYEVSEG TTIDLLQKAF AKLMARKKVK KIKKIKRKII
     PERYTIKEEI ENIEHTLKMH KGTMNFTDLF DFDGEVEVEK VVTSFLALLE LVRVGRVSAS
     QEENNGPILM TYEGKAEEDA I