ID   SCPA_LISMO              Reviewed;         249 AA.
AC   Q8Y5V4;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=lmo1951;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
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DR   EMBL; AL591981; CAD00029.1; -; Genomic_DNA.
DR   PIR; AG1318; AG1318.
DR   RefSeq; NP_465475.1; NC_003210.1.
DR   RefSeq; WP_003723598.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y5V4; -.
DR   SMR; Q8Y5V4; -.
DR   STRING; 169963.lmo1951; -.
DR   PaxDb; Q8Y5V4; -.
DR   EnsemblBacteria; CAD00029; CAD00029; CAD00029.
DR   GeneID; 987973; -.
DR   KEGG; lmo:lmo1951; -.
DR   PATRIC; fig|169963.11.peg.1998; -.
DR   eggNOG; COG1354; Bacteria.
DR   HOGENOM; CLU_038686_3_1_9; -.
DR   OMA; YLVMAAM; -.
DR   PhylomeDB; Q8Y5V4; -.
DR   BioCyc; LMON169963:LMO1951-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.580; -; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..249
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_0000211092"
SQ   SEQUENCE   249 AA;  29157 MW;  DF139D88AC380026 CRC64;
     MVEMNFKVDA FEGPLDLLLH LIGQLEVDIY DIPMAEITDQ YMEFVHTMQE MELDVASEYL
     VMAATLLAIK SKMLLPKQEL EIDYDTLEEE EDPRDALVEK LMEYKRFKEA AKELKEKEAE
     RSFYFSKPPM DLAEYDDGTK VAELDVSLND MLSAFNKMLR RKKLNKPLHT RITTQEISID
     QRMDSVLEKL NLQVNHRLRF DELFEEQTKE QLVVTFLALL ELMKRKLVEV EQAESFADLY
     VQGKGEEIS