ID   SCPA_STRA3              Reviewed;         235 AA.
AC   Q7ZAL5;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=gbs1644;
OS   Streptococcus agalactiae serotype III (strain NEM316).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=211110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEM316;
RX   PubMed=12354221; DOI=10.1046/j.1365-2958.2002.03126.x;
RA   Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T.,
RA   Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F.;
RT   "Genome sequence of Streptococcus agalactiae, a pathogen causing invasive
RT   neonatal disease.";
RL   Mol. Microbiol. 45:1499-1513(2002).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01805}.
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DR   EMBL; AL766852; CAD47303.1; -; Genomic_DNA.
DR   RefSeq; WP_000351874.1; NC_004368.1.
DR   AlphaFoldDB; Q7ZAL5; -.
DR   SMR; Q7ZAL5; -.
DR   STRING; 211110.gbs1644; -.
DR   EnsemblBacteria; CAD47303; CAD47303; CAD47303.
DR   KEGG; san:gbs1644; -.
DR   eggNOG; COG1354; Bacteria.
DR   HOGENOM; CLU_038686_3_3_9; -.
DR   OMA; YLVMAAM; -.
DR   Proteomes; UP000000823; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   PANTHER; PTHR33969; PTHR33969; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm.
FT   CHAIN           1..235
FT                   /note="Segregation and condensation protein A"
FT                   /id="PRO_0000211110"
SQ   SEQUENCE   235 AA;  27704 MW;  EF2EEF1DC1C53F7B CRC64;
     MDIKLKDFEG PLDLLLHLVS KYEVDIYDVP IVEVIEQYLA YIATLQAMRL EVAGEYMLMA
     SQLMLIKSRN LLPKVVESTP IEDDPEMELL SQLEEYRRFK VLSEELANQH QERAKYFSKP
     KQEVIFEDAI LLHDKSVMDL FLTFSQMMSQ KQKELSNSQT VIEKEDYRIE DMMIVIERHF
     NLKKKTTLQE VFADCQTKSE MITLFLAMLE LIKLHQITVE QDSNFSQVIL RKEEK