SCPB_BACCR
ID SCPB_BACCR Reviewed; 190 AA.
AC Q819C8;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Segregation and condensation protein B {ECO:0000255|HAMAP-Rule:MF_01804};
GN Name=scpB {ECO:0000255|HAMAP-Rule:MF_01804}; OrderedLocusNames=BC_4057;
OS Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=226900;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373
RC / NCTC 2599 / NRRL B-3711;
RX PubMed=12721630; DOI=10.1038/nature01582;
RA Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
RT "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT anthracis.";
RL Nature 423:87-91(2003).
CC -!- FUNCTION: Participates in chromosomal partition during cell division.
CC May act via the formation of a condensin-like complex containing Smc
CC and ScpA that pull DNA away from mid-cell into both cell halves.
CC {ECO:0000255|HAMAP-Rule:MF_01804}.
CC -!- SUBUNIT: Homodimer. Homodimerization may be required to stabilize the
CC binding of ScpA to the Smc head domains. Component of a cohesin-like
CC complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and
CC ScpB bind to the head domain of Smc. The presence of the three proteins
CC is required for the association of the complex with DNA.
CC {ECO:0000255|HAMAP-Rule:MF_01804}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01804}.
CC Note=Associated with two foci at the outer edges of the nucleoid region
CC in young cells, and at four foci within both cell halves in older
CC cells. {ECO:0000255|HAMAP-Rule:MF_01804}.
CC -!- SIMILARITY: Belongs to the ScpB family. {ECO:0000255|HAMAP-
CC Rule:MF_01804}.
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DR EMBL; AE016877; AAP10976.1; -; Genomic_DNA.
DR RefSeq; NP_833775.1; NC_004722.1.
DR RefSeq; WP_000375167.1; NC_004722.1.
DR AlphaFoldDB; Q819C8; -.
DR SMR; Q819C8; -.
DR STRING; 226900.BC_4057; -.
DR EnsemblBacteria; AAP10976; AAP10976; BC_4057.
DR KEGG; bce:BC4057; -.
DR PATRIC; fig|226900.8.peg.4188; -.
DR HOGENOM; CLU_045647_5_3_9; -.
DR OMA; DGWRFYT; -.
DR Proteomes; UP000001417; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051304; P:chromosome separation; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 2.
DR HAMAP; MF_01804; ScpB; 1.
DR InterPro; IPR005234; ScpB_csome_segregation.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR34298; PTHR34298; 1.
DR Pfam; PF04079; SMC_ScpB; 1.
DR PIRSF; PIRSF019345; ScpB; 1.
DR SUPFAM; SSF46785; SSF46785; 2.
DR TIGRFAMs; TIGR00281; TIGR00281; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW Reference proteome.
FT CHAIN 1..190
FT /note="Segregation and condensation protein B"
FT /id="PRO_0000211124"
SQ SEQUENCE 190 AA; 21562 MW; 1B4969E33760A658 CRC64;
MDRKEQKSII EGLLFVSGDE GIYPEQIAKV LEIEMNEAIN ILEEMQQECE GANRGLQIVQ
YAKVYRFATK KEHASYYQKL IDTPTAASLS QAALETLAIV AYRQPITRTE MEEIRGVKTD
KALQTLVSHL LIKEMGRAEG PGRPILYGTT KEFLDTFGLK TLDDLPPLSE ENEQMNEADL
FFGCLQEIWK
