ID   SCPB_CLOPE              Reviewed;         195 AA.
AC   Q46206; Q8XJF5;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-JAN-2004, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Segregation and condensation protein B {ECO:0000255|HAMAP-Rule:MF_01804};
GN   Name=scpB {ECO:0000255|HAMAP-Rule:MF_01804}; Synonyms=hypB;
GN   OrderedLocusNames=CPE1804;
OS   Clostridium perfringens (strain 13 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13 / Type A;
RX   PubMed=11792842; DOI=10.1073/pnas.022493799;
RA   Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA   Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT   "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT   eater.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 87-142.
RC   STRAIN=CPN50;
RX   PubMed=7559358; DOI=10.1128/jb.177.19.5680-5685.1995;
RA   Katayama S., Dupuy B., Garnier T., Cole S.T.;
RT   "Rapid expansion of the physical and genetic map of the chromosome of
RT   Clostridium perfringens CPN50.";
RL   J. Bacteriol. 177:5680-5685(1995).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpA that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SUBUNIT: Homodimer. Homodimerization may be required to stabilize the
CC       binding of ScpA to the Smc head domains. Component of a cohesin-like
CC       complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and
CC       ScpB bind to the head domain of Smc. The presence of the three proteins
CC       is required for the association of the complex with DNA.
CC       {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01804}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SIMILARITY: Belongs to the ScpB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01804}.
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DR   EMBL; BA000016; BAB81510.1; -; Genomic_DNA.
DR   EMBL; X86496; CAA60218.1; -; Genomic_DNA.
DR   RefSeq; WP_003451108.1; NC_003366.1.
DR   AlphaFoldDB; Q46206; -.
DR   SMR; Q46206; -.
DR   STRING; 195102.gene:10491068; -.
DR   EnsemblBacteria; BAB81510; BAB81510; BAB81510.
DR   GeneID; 29570839; -.
DR   KEGG; cpe:CPE1804; -.
DR   HOGENOM; CLU_045647_5_3_9; -.
DR   OMA; DGWRFYT; -.
DR   Proteomes; UP000000818; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051304; P:chromosome separation; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_01804; ScpB; 1.
DR   InterPro; IPR005234; ScpB_csome_segregation.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR34298; PTHR34298; 1.
DR   Pfam; PF04079; SMC_ScpB; 1.
DR   PIRSF; PIRSF019345; ScpB; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
DR   TIGRFAMs; TIGR00281; TIGR00281; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..195
FT                   /note="Segregation and condensation protein B"
FT                   /id="PRO_0000211129"
FT   CONFLICT        87
FT                   /note="E -> P (in Ref. 2; CAA60218)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        142
FT                   /note="N -> I (in Ref. 2; CAA60218)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   195 AA;  22308 MW;  DD6E2168576621B2 CRC64;
     MSDINQIEFS EISKKDELKS IIESLLFVSG EPLALKDICR IVEEDFKYVE DLMRELMNIY
     NGDSSRGIKI ISLNGTYQLV TKTKNSEYVQ KLLKKNVRQS LSQASLESLA IICYKQPITR
     VEIDEIRGVK SESAIQRLVE KNLVEETGRL EVPGRPILYG TTDEFLRHFA LNDLGDLPSI
     ELFEENDEVS DMVEE