ID   SCPB_MYCGA              Reviewed;         291 AA.
AC   Q7NB77;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Segregation and condensation protein B {ECO:0000255|HAMAP-Rule:MF_01804};
GN   Name=scpB {ECO:0000255|HAMAP-Rule:MF_01804}; OrderedLocusNames=MYCGA4020;
GN   ORFNames=MGA_0035;
OS   Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS   (Mycoplasmoides gallisepticum).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=710127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R(low / passage 15 / clone 2);
RX   PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA   Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA   Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT   "The complete genome sequence of the avian pathogen Mycoplasma
RT   gallisepticum strain R(low).";
RL   Microbiology 149:2307-2316(2003).
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpA that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SUBUNIT: Homodimer. Homodimerization may be required to stabilize the
CC       binding of ScpA to the Smc head domains. Component of a cohesin-like
CC       complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and
CC       ScpB bind to the head domain of Smc. The presence of the three proteins
CC       is required for the association of the complex with DNA.
CC       {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01804}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000255|HAMAP-Rule:MF_01804}.
CC   -!- SIMILARITY: Belongs to the ScpB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01804}.
CC   -!- CAUTION: Differs from other ScpB proteins because it has a longer N-
CC       terminus. {ECO:0000305}.
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DR   EMBL; AE015450; AAP56752.1; -; Genomic_DNA.
DR   RefSeq; WP_011113648.1; NC_004829.2.
DR   AlphaFoldDB; Q7NB77; -.
DR   SMR; Q7NB77; -.
DR   KEGG; mga:MGA_0035; -.
DR   PATRIC; fig|233150.7.peg.452; -.
DR   HOGENOM; CLU_955863_0_0_14; -.
DR   OMA; HAMIRRR; -.
DR   OrthoDB; 1771906at2; -.
DR   Proteomes; UP000001418; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051304; P:chromosome separation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_01804; ScpB; 1.
DR   InterPro; IPR005234; ScpB_csome_segregation.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR34298; PTHR34298; 1.
DR   Pfam; PF04079; SMC_ScpB; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
DR   TIGRFAMs; TIGR00281; TIGR00281; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   Reference proteome.
FT   CHAIN           1..291
FT                   /note="Segregation and condensation protein B"
FT                   /id="PRO_0000211138"
SQ   SEQUENCE   291 AA;  33663 MW;  C9CC03FA4400E019 CRC64;
     MKTKIKKITK KFNLKKDTEV KPLSTQELIE EQKEFSQAVD KLMTKKQKPT FEDIGSSIVD
     FETSDNDKFY ESVRDAIEKT SEIVDDLDQS ELTKNSYEQK ELSAKAIIQA ALYVAGRNGM
     TLQELNKILP KIHQDQLFKE LEEMIYSYDQ NLNFGLTIKN YGGRYKILTK AAVKKDMQRY
     VSERFKNPLN KSLMEVLAIV AYNQPCTRVR INEIRGVDSL SLVDNLLEKG LIVEVGRADT
     PGRPFLYNVS EKFFDLFGIE SIDDLPQIKH FDPDSYQEGD FFDSNRYDEN E