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SCPB_PENSP
ID   SCPB_PENSP              Reviewed;         192 AA.
AC   P02635;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Sarcoplasmic calcium-binding protein, beta chain;
DE            Short=SCP beta chain;
OS   Penaeus sp. (Penoeid shrimp).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; unclassified Penaeidae.
OX   NCBI_TaxID=6688;
RN   [1]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT ALA-1.
RX   PubMed=6490607; DOI=10.1093/oxfordjournals.jbchem.a134829;
RA   Takagi T., Konishi K.;
RT   "Amino acid sequence of the beta chain of sarcoplasmic calcium binding
RT   protein (SCP) obtained from shrimp tail muscle.";
RL   J. Biochem. 96:59-67(1984).
CC   -!- FUNCTION: Like parvalbumins, SCPs seem to be more abundant in fast
CC       contracting muscles, but no functional relationship can be established
CC       from this distribution.
CC   -!- SUBUNIT: SCPs from crayfish, lobster, and shrimp are polymorphic
CC       dimers; three isotypes (alpha-alpha, alpha-beta, and beta-beta) have
CC       been identified.
CC   -!- MISCELLANEOUS: The sarcoplasmic calcium-binding proteins are abundant
CC       in the muscle of arthropods, mollusks, annelids, and protochordates.
CC   -!- MISCELLANEOUS: This protein has three functional calcium-binding sites;
CC       potential site 4 has lost affinity for calcium.
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DR   PIR; A03072; KLSSBS.
DR   AlphaFoldDB; P02635; -.
DR   SMR; P02635; -.
DR   iPTMnet; P02635; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF13202; EF-hand_5; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 3.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 3.
DR   PROSITE; PS50222; EF_HAND_2; 3.
PE   1: Evidence at protein level;
KW   Acetylation; Calcium; Direct protein sequencing; Metal-binding;
KW   Muscle protein; Repeat.
FT   CHAIN           1..192
FT                   /note="Sarcoplasmic calcium-binding protein, beta chain"
FT                   /id="PRO_0000073635"
FT   DOMAIN          4..39
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          56..91
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          100..135
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          136..171
FT                   /note="EF-hand 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         17
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         19
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         21
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         28
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         69
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         71
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         73
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         75
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         80
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         113
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         115
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         117
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         119
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         124
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   MOD_RES         1
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000269|PubMed:6490607"
SQ   SEQUENCE   192 AA;  21968 MW;  838123A824E33445 CRC64;
     AYSWDNRVKY IVRYMYDIDN DGFLDKNDFE CLAVRVTLIE GRGEFSPEGY AKNKEIMANL
     WNEIAELADF NKDGEVTVDE FKQAVQKNCK GKAFANFPNA FKVFIGNQFK TIDVDGDGMV
     GVDEYRLDCI TRSAFADVKE IDDAYDKLCT EEDKKAGGIN LARYQELYAQ FISNEDEKNN
     ACYLFGPLKE VQ
 
 
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