SCPDL_ARATH
ID SCPDL_ARATH Reviewed; 454 AA.
AC Q8LGI2; Q9ZR98;
DT 07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 2.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Probable mitochondrial saccharopine dehydrogenase-like oxidoreductase At5g39410;
DE Short=SDH;
DE EC=1.-.-.-;
GN OrderedLocusNames=At5g39410; ORFNames=MUL8.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Lessard P., Petit-Jean X., Kreis M., Thomas M.;
RL Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14671022; DOI=10.1105/tpc.016055;
RA Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J.,
RA Millar A.H.;
RT "Experimental analysis of the Arabidopsis mitochondrial proteome highlights
RT signaling and regulatory components, provides assessment of targeting
RT prediction programs, and indicates plant-specific mitochondrial proteins.";
RL Plant Cell 16:241-256(2004).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC {ECO:0000269|PubMed:14671022}.
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U83179; AAD09232.1; -; mRNA.
DR EMBL; AB009054; BAB11014.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94430.1; -; Genomic_DNA.
DR EMBL; AY084257; AAM60851.1; -; mRNA.
DR RefSeq; NP_568564.1; NM_123303.4.
DR AlphaFoldDB; Q8LGI2; -.
DR BioGRID; 19188; 2.
DR STRING; 3702.AT5G39410.1; -.
DR iPTMnet; Q8LGI2; -.
DR PaxDb; Q8LGI2; -.
DR PRIDE; Q8LGI2; -.
DR ProteomicsDB; 232856; -.
DR DNASU; 833937; -.
DR EnsemblPlants; AT5G39410.1; AT5G39410.1; AT5G39410.
DR GeneID; 833937; -.
DR Gramene; AT5G39410.1; AT5G39410.1; AT5G39410.
DR KEGG; ath:AT5G39410; -.
DR Araport; AT5G39410; -.
DR TAIR; locus:2175723; AT5G39410.
DR eggNOG; KOG2733; Eukaryota.
DR HOGENOM; CLU_031002_1_1_1; -.
DR InParanoid; Q8LGI2; -.
DR OMA; RTYFKMT; -.
DR OrthoDB; 887497at2759; -.
DR PhylomeDB; Q8LGI2; -.
DR PRO; PR:Q8LGI2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8LGI2; baseline and differential.
DR Genevisible; Q8LGI2; AT.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0005811; C:lipid droplet; IBA:GO_Central.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009247; P:glycolipid biosynthetic process; IBA:GO_Central.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 1: Evidence at protein level;
KW Acetylation; Membrane; Mitochondrion; Oxidoreductase; Reference proteome.
FT CHAIN 1..454
FT /note="Probable mitochondrial saccharopine dehydrogenase-
FT like oxidoreductase At5g39410"
FT /id="PRO_0000226069"
FT REGION 215..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CONFLICT 8
FT /note="E -> D (in Ref. 4; AAM60851)"
FT /evidence="ECO:0000305"
FT CONFLICT 13
FT /note="M -> I (in Ref. 4; AAM60851)"
FT /evidence="ECO:0000305"
FT CONFLICT 38
FT /note="Missing (in Ref. 4)"
FT /evidence="ECO:0000305"
FT CONFLICT 136
FT /note="N -> K (in Ref. 4; AAM60851)"
FT /evidence="ECO:0000305"
FT CONFLICT 403
FT /note="V -> L (in Ref. 4; AAM60851)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 454 AA; 49681 MW; 7020142459682B6B CRC64;
MNPTQKPEPV YDMVILGASG FTGKYVVREA LKFLQTPSSS PLKSLALAGR NPTRLTQSLE
WAARPNPPPS SVAILTADTS DPDSLRRLCT QTKLILNCVG PFRIHGDPVV SACADSGCDY
LDISGEPEFM ERMEANYHDR AEETGSLIVS ACGFDSIPAE LGLLFNAKQW VSPSVPNQIE
AYLSLESDKK IAGNFGTYES AVLGVANAEK LKELRRSRPR RPRPTICGPP AKGPTLENQK
TIGLWALKLP SADAVVVRRT LTTLTEKPHG LPGINESPEQ IQKREAFWSS IKPAHFGVKI
TSKSLFGIFR YVTLGVSLGL LSKFSFGRWL LLKFPSVFSL GWFQKKGPSE EEVESATFKM
WFIGRGYSEE SLASQGETKP DLEIITRISG PEIGYITTPI TLVQCGLIVL GQRESLVKGG
VYTPGIVFGS TDIQQRLEDN GISFELISKI KTQG
