ID   SCPDL_RAT               Reviewed;         429 AA.
AC   Q6AY30;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Saccharopine dehydrogenase-like oxidoreductase;
DE            EC=1.-.-.-;
GN   Name=Sccpdh;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209; SER-215 AND SER-217, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000305}.
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DR   EMBL; BC079215; AAH79215.1; -; mRNA.
DR   RefSeq; NP_001014007.1; NM_001013985.1.
DR   RefSeq; XP_008768101.2; XM_008769879.2.
DR   RefSeq; XP_017460149.1; XM_017604660.1.
DR   AlphaFoldDB; Q6AY30; -.
DR   SMR; Q6AY30; -.
DR   BioGRID; 258053; 2.
DR   STRING; 10116.ENSRNOP00000003791; -.
DR   iPTMnet; Q6AY30; -.
DR   PhosphoSitePlus; Q6AY30; -.
DR   jPOST; Q6AY30; -.
DR   PaxDb; Q6AY30; -.
DR   PRIDE; Q6AY30; -.
DR   Ensembl; ENSRNOT00000003791; ENSRNOP00000003791; ENSRNOG00000066712.
DR   GeneID; 305021; -.
DR   KEGG; rno:305021; -.
DR   UCSC; RGD:1311440; rat.
DR   CTD; 51097; -.
DR   RGD; 1311440; Sccpdh.
DR   eggNOG; KOG2733; Eukaryota.
DR   GeneTree; ENSGT00390000004799; -.
DR   HOGENOM; CLU_031002_1_0_1; -.
DR   InParanoid; Q6AY30; -.
DR   OMA; KQIGHKP; -.
DR   OrthoDB; 887497at2759; -.
DR   PhylomeDB; Q6AY30; -.
DR   TreeFam; TF314904; -.
DR   Reactome; R-RNO-114608; Platelet degranulation.
DR   PRO; PR:Q6AY30; -.
DR   Proteomes; UP000002494; Chromosome 13.
DR   Bgee; ENSRNOG00000037984; Expressed in cerebellum and 18 other tissues.
DR   Genevisible; Q6AY30; RN.
DR   GO; GO:0005811; C:lipid droplet; ISO:RGD.
DR   GO; GO:0030496; C:midbody; ISO:RGD.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009247; P:glycolipid biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Oxidoreductase; Phosphoprotein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NBX0"
FT   CHAIN           2..429
FT                   /note="Saccharopine dehydrogenase-like oxidoreductase"
FT                   /id="PRO_0000212843"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NBX0"
FT   MOD_RES         209
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         215
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         217
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   429 AA;  47088 MW;  D16F3BE0BBF8D300 CRC64;
     MATEQRPFQL VVFGASGFTG QFVTEEVARE QMASEQSSRL PWAVAGRSKE KLQQVLEKAA
     QKLGRATLSS EVGIIICDIS NPASLDEMAK KATLVLNCVG PYRFYGEPVV KACIENGTSC
     IDICGEPQFL ELMHVKYHEK AAEKGVYIIG SSGFDSIPAD LGVLYTRNQM NGTLTAVESF
     LTINSGPEGL CIHDGTWKSA IYGFGDKGSL RKLRSVSNLK PVPVIGSKLK RRWPVSYCRE
     LNSYAIPFLG SDMSVVKRTQ RYLHENLEDS PVQYAAYITV GGITSVIKLM FAGLFFLFFV
     KFSIGRQLLV KFPWLFSFGY FSKRGPTQKQ MDESSFTMTF FGQGYSHGVS AEKNKPNIRI
     CTQVKGPEAG YVATPIAMVQ AAVTFLNDAS DLPKGGGVFT PGAAFSRTKL IDRLNQHGIQ
     FSVISSSEV