SCRK2_SOLLC
ID SCRK2_SOLLC Reviewed; 328 AA.
AC Q42896; O04994;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Fructokinase-2;
DE EC=2.7.1.4;
GN Name=FRK2;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Martinez-Barajas E., Luethy M.H., Randall D.D.;
RT "Molecular cloning and analysis of fructokinase expression in tomato
RT (Lycopersicon esculentum Mill.).";
RL Plant Sci. 125:13-20(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=9112782; DOI=10.1104/pp.113.4.1379;
RA Kanayama Y., Dai N., Granot D., Petreikov M., Schaffer A., Bennett A.B.;
RT "Divergent fructokinase genes are differentially expressed in tomato.";
RL Plant Physiol. 113:1379-1384(1997).
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000305}.
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DR EMBL; U62329; AAB51108.1; -; mRNA.
DR EMBL; U64818; AAB57734.1; -; mRNA.
DR RefSeq; NP_001233888.1; NM_001246959.2.
DR AlphaFoldDB; Q42896; -.
DR SMR; Q42896; -.
DR STRING; 4081.Solyc06g073190.2.1; -.
DR PaxDb; Q42896; -.
DR PRIDE; Q42896; -.
DR ProMEX; Q42896; -.
DR EnsemblPlants; Solyc06g073190.3.1; Solyc06g073190.3.1; Solyc06g073190.3.
DR GeneID; 544022; -.
DR Gramene; Solyc06g073190.3.1; Solyc06g073190.3.1; Solyc06g073190.3.
DR KEGG; sly:544022; -.
DR eggNOG; KOG2855; Eukaryota.
DR HOGENOM; CLU_027634_6_1_1; -.
DR InParanoid; Q42896; -.
DR OMA; GAWPEYP; -.
DR OrthoDB; 918144at2759; -.
DR PhylomeDB; Q42896; -.
DR BRENDA; 2.7.1.4; 3101.
DR UniPathway; UPA00152; -.
DR Proteomes; UP000004994; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008865; F:fructokinase activity; IBA:GO_Central.
DR GO; GO:0006000; P:fructose metabolic process; IBA:GO_Central.
DR GO; GO:0019252; P:starch biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; SSF53613; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW Reference proteome; Transferase.
FT CHAIN 1..328
FT /note="Fructokinase-2"
FT /id="PRO_0000252670"
SQ SEQUENCE 328 AA; 34763 MW; B4EA6456D439B4F4 CRC64;
MAVNGASSSG LIVSFGEMLI DFVPTVSGVS LAEAPGFLKA PGGAPANVAI AVTRLGGKSA
FVGKLGDDEF GHMLAGILKT NGVQAEGINF DKGARTALAF VTLRADGERE FMFYRNPSAD
MLLTPAELNL DLIRSAKVFH YGSISLIVEP CRAAHMKAME VAKEAGALLS YDPNLRLPLW
PSAEEAKKQI KSIWDSADVI KVSDVELEFL TGSNKIDDES AMSLWHPNLK LLLVTLGEKG
CNYYTKKFHG TVGGFHVKTV DTTGAGDSFV GALLTKIVDD QTILEDEARL KEVLRFSCAC
GAITTTKKGA IPALPTASEA LTLLKGGA
