SCRK3_ARATH
ID SCRK3_ARATH Reviewed; 345 AA.
AC Q9LNE4;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Probable fructokinase-3;
DE EC=2.7.1.4;
GN OrderedLocusNames=At1g06020 {ECO:0000312|Araport:AT1G06020};
GN ORFNames=T21E18.7 {ECO:0000312|EMBL:AAF80125.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000250|UniProtKB:Q6XZ79}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000305}.
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DR EMBL; AC024174; AAF80125.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27930.1; -; Genomic_DNA.
DR EMBL; DQ056446; AAY78603.1; -; mRNA.
DR PIR; C86195; C86195.
DR RefSeq; NP_172092.1; NM_100482.2.
DR AlphaFoldDB; Q9LNE4; -.
DR SMR; Q9LNE4; -.
DR BioGRID; 22353; 5.
DR STRING; 3702.AT1G06020.1; -.
DR PaxDb; Q9LNE4; -.
DR PRIDE; Q9LNE4; -.
DR ProteomicsDB; 232773; -.
DR EnsemblPlants; AT1G06020.1; AT1G06020.1; AT1G06020.
DR GeneID; 837111; -.
DR Gramene; AT1G06020.1; AT1G06020.1; AT1G06020.
DR KEGG; ath:AT1G06020; -.
DR Araport; AT1G06020; -.
DR TAIR; locus:2198821; AT1G06020.
DR eggNOG; KOG2855; Eukaryota.
DR HOGENOM; CLU_027634_6_1_1; -.
DR InParanoid; Q9LNE4; -.
DR OMA; GDEFGHM; -.
DR OrthoDB; 918144at2759; -.
DR PhylomeDB; Q9LNE4; -.
DR BioCyc; ARA:AT1G06020-MON; -.
DR BRENDA; 2.7.1.4; 399.
DR UniPathway; UPA00152; -.
DR PRO; PR:Q9LNE4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LNE4; baseline and differential.
DR Genevisible; Q9LNE4; AT.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008865; F:fructokinase activity; IDA:TAIR.
DR GO; GO:0006000; P:fructose metabolic process; IDA:TAIR.
DR GO; GO:0019252; P:starch biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; SSF53613; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW Reference proteome; Transferase.
FT CHAIN 1..345
FT /note="Probable fructokinase-3"
FT /id="PRO_0000237603"
SQ SEQUENCE 345 AA; 37628 MW; 7D2F453E14B813C9 CRC64;
MASSTGEKGL IVSFGEMLID FVPTVSGVSL SESPGFLKAP GGAPANVAIA VSRLGGRAAF
VGKLGDDDFG HMLAGILRKN GVDDQGINFD EGARTALAFV TLRSDGEREF MFYRNPSADM
LLRPDELNLE LIRSAKVFHY GSISLITEPC RSAHMKAMEV AKEAGALLSY DPNLREPLWP
SPEEARTQIM SIWDKADIIK VSDVELEFLT ENKTMDDKTA MSLWHPNLKL LLVTLGEKGC
TYFTKKFHGS VETFHVDAVD TTGAGDSFVG ALLQQIVDDQ SVLEDEARLR KVLRFANACG
AITTTKKGAI PALPTDIEAL SFLKDQKKRQ TNLKFSKWCC TASPC
