SCRK8_ARATH
ID SCRK8_ARATH Reviewed; 210 AA.
AC Q9SX54;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 29-OCT-2014, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Putative fructokinase-8;
DE EC=2.7.1.4;
GN OrderedLocusNames=At1g50390 {ECO:0000312|Araport:AT1G50390};
GN ORFNames=F14I3.3 {ECO:0000312|EMBL:AAD50037.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000250|UniProtKB:Q6XZ79}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD50037.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAD50037.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
CC Sequence=AEE32543.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AEE32543.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC007980; AAD50037.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE32543.1; ALT_SEQ; Genomic_DNA.
DR PIR; B96540; B96540.
DR RefSeq; NP_175456.1; NM_103922.1.
DR AlphaFoldDB; Q9SX54; -.
DR SMR; Q9SX54; -.
DR BioGRID; 26686; 4.
DR PeptideAtlas; Q9SX54; -.
DR PRIDE; Q9SX54; -.
DR GeneID; 841461; -.
DR KEGG; ath:AT1G50390; -.
DR Araport; AT1G50390; -.
DR TAIR; locus:2011897; AT1G50390.
DR HOGENOM; CLU_027634_17_1_1; -.
DR InParanoid; Q9SX54; -.
DR OrthoDB; 918144at2759; -.
DR BioCyc; ARA:AT1G50390-MON; -.
DR UniPathway; UPA00152; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SX54; baseline and differential.
DR Genevisible; Q9SX54; AT.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008865; F:fructokinase activity; IBA:GO_Central.
DR GO; GO:0006000; P:fructose metabolic process; IBA:GO_Central.
DR GO; GO:0019252; P:starch biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR Pfam; PF00294; PfkB; 1.
DR SUPFAM; SSF53613; SSF53613; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 5: Uncertain;
KW ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW Reference proteome; Transferase.
FT CHAIN 1..210
FT /note="Putative fructokinase-8"
FT /id="PRO_0000430868"
SQ SEQUENCE 210 AA; 23467 MW; 0B1E915B3AB10C59 CRC64;
MILKSQANKL KFTKQAKVFH YGSISLITEP CRSAHMKATE EAKEAGALLS YDPNLREPLW
PSPEEARTQI MSIWDKADII KVSDVELEFL TRNKTIDDET AMSLWHPNLK LLLVTLGEKG
CRYYTKDFHG SVETFHVDAV DTTGAGDSFV GALLNQIVDD QSVLEEEERL RKVLRIANAC
GAITTTKKGA IPALPTDCEA LSFLKRQVEQ
