ID   SCRK_RHILT              Reviewed;         326 AA.
AC   P42720;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Fructokinase;
DE            EC=2.7.1.4;
GN   Name=frk;
OS   Rhizobium leguminosarum bv. trifolii.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8932706; DOI=10.1099/13500872-142-2-321;
RA   Fennington G.J., Hughes T.A.;
RT   "The fructokinase from Rhizobium leguminosarum biovar trifolii belongs to
RT   group I fructokinase enzymes and is encoded separately from other
RT   carbohydrate metabolism enzymes.";
RL   Microbiology 142:321-330(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC         Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000305}.
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DR   EMBL; U08434; AAB52373.1; -; Unassigned_DNA.
DR   AlphaFoldDB; P42720; -.
DR   SMR; P42720; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   Pfam; PF00294; PfkB; 1.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..326
FT                   /note="Fructokinase"
FT                   /id="PRO_0000080136"
FT   REGION          275..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  35469 MW;  8F8ACBDF259CE285 CRC64;
     MILCCGEALI DMLPRDTTLG EKGFAPYAGG AIFNTAIALG RLGIPTAFFT GIADDMMGEI
     LLETLKASNV DYSPCAITPR PSTIAFVKLV NGQATYAFYD EGTAGRMITT ADLPDLGDDC
     EALHFGAISL IPSPCGETYE ALLDREAASR VISLDPNIRP GFIKDKPSHM ARIKRMAAKS
     DIVKFSDEDL DWFGLQGDHD ALAAHWLNHG AKLVVITKGA EGASGYTKDR KVTVPSERVT
     VVDTVGAGDT FDAGILASLK MDNLLTKRQV ASLDEQALRN GPDPRRQSRR RHRLPRRRQS
     TLGARDWSLR LEQDSDPHPP DDTFSP