ID   SCRK_SALTM              Reviewed;         307 AA.
AC   P26984;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Fructokinase;
DE            EC=2.7.1.4;
GN   Name=scrK;
OS   Salmonella typhimurium.
OG   Plasmid pUR400.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90371;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1809835; DOI=10.1111/j.1365-2958.1991.tb01851.x;
RA   Aulkemeyer P., Ebner R., Heilenmann G., Jahreis K., Schmid K., Wrieden S.,
RA   Lengeler J.W.;
RT   "Molecular analysis of two fructokinases involved in sucrose metabolism of
RT   enteric bacteria.";
RL   Mol. Microbiol. 5:2913-2922(1991).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC         Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000305}.
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DR   EMBL; X61005; CAA43323.1; -; Genomic_DNA.
DR   PIR; S18524; S18524.
DR   AlphaFoldDB; P26984; -.
DR   SMR; P26984; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR002139; Ribo/fructo_kinase.
DR   InterPro; IPR029056; Ribokinase-like.
DR   Pfam; PF00294; PfkB; 1.
DR   PRINTS; PR00990; RIBOKINASE.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   PROSITE; PS00583; PFKB_KINASES_1; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding; Plasmid;
KW   Transferase.
FT   CHAIN           1..307
FT                   /note="Fructokinase"
FT                   /id="PRO_0000080138"
SQ   SEQUENCE   307 AA;  32916 MW;  E01CB770CE20B329 CRC64;
     MNAKVWVLGD AVVDLLPESE GRLLQCPGGA PANVAVGVAR LGGNSGFIGA VGGDPFGRYM
     RHTLQQEQVD VSHMYLDDQH RTSTVVVDLD DQGERTFTFM VRPSADLFLV EEDLPQFAAG
     QWLHVCSIAL SAEPSRSTTF AAMESIRSAG GRVSFDPNIR PDLWQDQALL LACLDRALHM
     ANVVKLSEEE LVFISSSNDL AYGIASVTER YQPELLLVTR GKAGVLAAFQ QKFTHFNARP
     VASVDTTGAG DAFVAGLLAS LAANGMPTDM TALEPTLTLA QTCGALATTA KGAMTALPYQ
     RDLNRQF