ID   SCRK_VIBAL              Reviewed;         307 AA.
AC   P22824;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Fructokinase;
DE            EC=2.7.1.4;
GN   Name=scrK;
OS   Vibrio alginolyticus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2174811; DOI=10.1016/0378-1119(90)90408-j;
RA   Blatch G.L., Scholle R.R., Woods D.R.;
RT   "Nucleotide sequence and analysis of the Vibrio alginolyticus sucrose
RT   uptake-encoding region.";
RL   Gene 95:17-23(1990).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC         Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000305}.
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DR   EMBL; M76768; AAA27556.1; -; Genomic_DNA.
DR   PIR; JQ0782; JQ0782.
DR   AlphaFoldDB; P22824; -.
DR   SMR; P22824; -.
DR   STRING; 663.BAU10_17440; -.
DR   eggNOG; COG0524; Bacteria.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR002139; Ribo/fructo_kinase.
DR   InterPro; IPR029056; Ribokinase-like.
DR   Pfam; PF00294; PfkB; 1.
DR   PRINTS; PR00990; RIBOKINASE.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   PROSITE; PS00583; PFKB_KINASES_1; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..307
FT                   /note="Fructokinase"
FT                   /id="PRO_0000080140"
SQ   SEQUENCE   307 AA;  33046 MW;  AF9C96CBB781C6EF CRC64;
     MNQVWVTGDA VVDLIPESET SLLKCPGGAP ANVAVAIARL SGKSAFFGRV GDDPFGRFMQ
     SILDQEGVCT EFLIKDPEQR TSTVVVDLDD QGERSFTFMV KPSADQFMSV EDMGNFKQGD
     WLHVCSISLA NEPSRSSTFE AIKRAKAAGG FISFDPNLRD EVWQDQSEIQ AVVMKAVAMA
     DVVKFSEEEL LFLTDSTSMA QGLQQIAAMN IALVLVTQGA KGVWRVFESQ SELITGQVVS
     PIDTTGAGDA FVGGLLACLS RHADWKNHPV VSSAIQWANG CGALATTQKG AMTALPTQTE
     LLRFIGQ