ID   SCRN2_RAT               Reviewed;         423 AA.
AC   Q6AYR8;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Secernin-2;
GN   Name=Scrn2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the peptidase C69 family. Secernin subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC078939; AAH78939.1; -; mRNA.
DR   RefSeq; NP_001012142.1; NM_001012142.1.
DR   RefSeq; XP_006247404.1; XM_006247342.3.
DR   RefSeq; XP_017452882.1; XM_017597393.1.
DR   AlphaFoldDB; Q6AYR8; -.
DR   SMR; Q6AYR8; -.
DR   STRING; 10116.ENSRNOP00000013580; -.
DR   MEROPS; C69.004; -.
DR   jPOST; Q6AYR8; -.
DR   PaxDb; Q6AYR8; -.
DR   PRIDE; Q6AYR8; -.
DR   Ensembl; ENSRNOT00000013580; ENSRNOP00000013580; ENSRNOG00000010214.
DR   GeneID; 360612; -.
DR   KEGG; rno:360612; -.
DR   UCSC; RGD:1307741; rat.
DR   CTD; 90507; -.
DR   RGD; 1307741; Scrn2.
DR   eggNOG; ENOG502QPIA; Eukaryota.
DR   GeneTree; ENSGT00390000013474; -.
DR   HOGENOM; CLU_046840_0_0_1; -.
DR   InParanoid; Q6AYR8; -.
DR   OMA; AKAQGWW; -.
DR   OrthoDB; 322959at2759; -.
DR   PhylomeDB; Q6AYR8; -.
DR   TreeFam; TF323890; -.
DR   PRO; PR:Q6AYR8; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000010214; Expressed in pancreas and 19 other tissues.
DR   Genevisible; Q6AYR8; RN.
DR   GO; GO:0070004; F:cysteine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR005322; Peptidase_C69.
DR   PANTHER; PTHR12994; PTHR12994; 1.
DR   Pfam; PF03577; Peptidase_C69; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..423
FT                   /note="Secernin-2"
FT                   /id="PRO_0000262554"
FT   ACT_SITE        12
FT                   /evidence="ECO:0000255"
FT   MOD_RES         52
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96FV2"
SQ   SEQUENCE   423 AA;  46502 MW;  6B71409229A4DC68 CRC64;
     MASSSPDAPC SCDCFVSVPP ASAIPAVIFA KNSDRPRDEV QEVVFIPAGT HTPGSRLQCT
     YIEVEQVWKT HAVILSRPSW LWGAEMGANE LGVCIGNEAV WTKEPVGEGE ALLGMDLLRL
     ALERSSTAQA AVHVIAGLLD RYGQGGSCRE DPEPFCYHNT FLLADRTEAW VLETAGRLWA
     AQRIQGGARN ISNQLSIGTD ISAEHPELRS HAKAQGWWSG QGVFDFAEVF SLTQQPVRME
     AAKARFRAGC EMLQRQQGSI TAEVMMDILR NKESGICMDS GGFRTTASMV SVLPQDPTKP
     CVHFLTATPD PSRSVFKPFI FEVGVSQPPQ VLSPTFGAQD PVRILPRFQT QVDRRHSLYR
     GHQAALGLMD EQEQAQLRQE QQSLEQEGLE ALRGLLTGEQ TPAPQELGSL FQAFVEREHQ
     VYA