ID   SCRR_PEDPE              Reviewed;         326 AA.
AC   P43472;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Sucrose operon repressor;
DE   AltName: Full=Scr operon regulatory protein;
GN   Name=scrR;
OS   Pediococcus pentosaceus.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Pediococcus.
OX   NCBI_TaxID=1255;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PPE1.0;
RA   Leenhouts K.K.J., Bolhuis A.A., Kok J.J., Venema G.G.;
RT   "The sucrose and raffinose operons of Pediococcus pentosaceus PPE1.0.";
RL   Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of scrB expression. {ECO:0000250}.
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DR   EMBL; Z32771; CAA83670.1; -; Genomic_DNA.
DR   EMBL; L32093; AAA25569.1; -; Genomic_DNA.
DR   PIR; S44259; S44259.
DR   AlphaFoldDB; P43472; -.
DR   SMR; P43472; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..326
FT                   /note="Sucrose operon repressor"
FT                   /id="PRO_0000108001"
FT   DOMAIN          1..57
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        5..24
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   326 AA;  36207 MW;  AE0179D1564F7920 CRC64;
     MKPKLNDVAK LAGVSATTVS RVINNHGYLS SQTKEKVFAA MRELHYQPNN MARSLQGKNT
     RLIGVIFSDI SNPFFGELVS RIEKILFAKN YKVILCNSAD DPQKERDYLQ MLMANQVDGI
     IAGAHNLGIE EYQQYGLPII SFDRYLSDNI PIVSSDNYQG GWLATQTLHQ AGATNVAIFT
     GKSHAGSPTN GRREGYEAYL TAQQLTPHVH ELPFELTPAL KMMEIKTIMT QHQYDGIFCS
     DDLAALLVLN VAQQLSLTVP EQLRVVGYDG TALIRDYHSE LTTVEQPLAD ISTLLVSLLL
     QRIEDANCTL ESKYTLPVKL IKGFTA