ID   SCRR_STAXY              Reviewed;         320 AA.
AC   P74892;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Sucrose operon repressor;
DE   AltName: Full=Scr operon regulatory protein;
GN   Name=scrR;
OS   Staphylococcus xylosus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1288;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 20267 / Isolate C2A;
RX   PubMed=8550467; DOI=10.1128/jb.178.2.462-469.1996;
RA   Gering M., Brueckner R.;
RT   "Transcriptional regulation of the sucrase gene of Staphylococcus xylosus
RT   by the repressor ScrR.";
RL   J. Bacteriol. 178:462-469(1996).
CC   -!- FUNCTION: Negative regulator of scrB expression.
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DR   EMBL; X67744; CAA47969.1; -; Genomic_DNA.
DR   RefSeq; WP_047172113.1; NZ_LN554884.1.
DR   AlphaFoldDB; P74892; -.
DR   SMR; P74892; -.
DR   STRING; 1288.SXYLSMQ121_0864; -.
DR   KEGG; sxo:SXYL_00886; -.
DR   eggNOG; COG1609; Bacteria.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..320
FT                   /note="Sucrose operon repressor"
FT                   /id="PRO_0000108002"
FT   DOMAIN          1..55
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        4..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   320 AA;  35816 MW;  4EE61828C9E4E88A CRC64;
     MKNIADIAKI AGVSKSTVSR YLNNGSVSLK TQQKLDEIIR ENDYQPNQFA QSLRARRTNM
     IGAIIPRMNS FAVDETIKGV KTVCDQLNYS LLLNYTNLNI QLEIDALETF YRSKVDGIVF
     MATEITDQHL EVINKINVPV IIVGQAHDDL HCIIHNDYQA GYLVGDMLGQ QGYNDIKFFG
     VTESDIAVGV QRKEGLIAGL EAHNIQPEIS LTSFNYQEAM VDVVEALQAY PHYDAIVGAT
     DSIALAIHKY NSEHKPHAHE KYIVGFGGDP VTDIVSPSIH TINYNFEYAG SVAMDKLNQM
     IQHQVIEQRI IIDVEQSFEN