ID   SCR_MAIZE               Reviewed;         668 AA.
AC   Q9FUZ7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Protein SCARECROW;
DE   AltName: Full=ZmSCR;
GN   Name=SCR;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, AND
RP   DEVELOPMENTAL STAGE.
RC   STRAIN=cv. B73;
RX   PubMed=10948251; DOI=10.2307/3871131;
RA   Lim J., Helariutta Y., Specht C.D., Jung J., Sims L., Bruce W.B., Diehn S.,
RA   Benfey P.N.;
RT   "Molecular analysis of the SCARECROW gene in maize reveals a common basis
RT   for radial patterning in diverse meristems.";
RL   Plant Cell 12:1307-1318(2000).
CC   -!- FUNCTION: Probable transcription factor involved in establishing and
CC       maintaining the correct radial pattern in the root apical meristem.
CC       {ECO:0000269|PubMed:10948251}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in the root endodermis and in a single
CC       file of cells through the quiescent center.
CC       {ECO:0000269|PubMed:10948251}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in early stages of lateral root
CC       primordium formation, becoming restricted to the endodermal cell
CC       lineage at later stages. {ECO:0000269|PubMed:10948251}.
CC   -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
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DR   EMBL; AF263457; AAG13663.1; -; Genomic_DNA.
DR   RefSeq; NP_001168484.1; NM_001175013.1.
DR   AlphaFoldDB; Q9FUZ7; -.
DR   SMR; Q9FUZ7; -.
DR   STRING; 4577.GRMZM2G131516_P02; -.
DR   PaxDb; Q9FUZ7; -.
DR   PRIDE; Q9FUZ7; -.
DR   EnsemblPlants; Zm00001eb195650_T001; Zm00001eb195650_P001; Zm00001eb195650.
DR   GeneID; 100382261; -.
DR   Gramene; Zm00001eb195650_T001; Zm00001eb195650_P001; Zm00001eb195650.
DR   KEGG; zma:100382261; -.
DR   MaizeGDB; 902852; -.
DR   eggNOG; ENOG502QTMY; Eukaryota.
DR   HOGENOM; CLU_011924_7_2_1; -.
DR   OMA; MEIQTGA; -.
DR   OrthoDB; 772613at2759; -.
DR   Proteomes; UP000007305; Chromosome 4.
DR   ExpressionAtlas; Q9FUZ7; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0008356; P:asymmetric cell division; IBA:GO_Central.
DR   GO; GO:0090610; P:bundle sheath cell fate specification; IBA:GO_Central.
DR   GO; GO:0009630; P:gravitropism; IBA:GO_Central.
DR   GO; GO:0048366; P:leaf development; IBA:GO_Central.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IBA:GO_Central.
DR   GO; GO:0009956; P:radial pattern formation; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR005202; TF_GRAS.
DR   PANTHER; PTHR31636; PTHR31636; 1.
DR   Pfam; PF03514; GRAS; 1.
DR   PROSITE; PS50985; GRAS; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Developmental protein; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..668
FT                   /note="Protein SCARECROW"
FT                   /id="PRO_0000329422"
FT   DOMAIN          290..660
FT                   /note="GRAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   REGION          217..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..361
FT                   /note="Leucine repeat I (LRI)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   REGION          380..445
FT                   /note="VHIID"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   REGION          455..487
FT                   /note="Leucine repeat II (LRII)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   REGION          496..583
FT                   /note="PFYRE"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   REGION          586..660
FT                   /note="SAW"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   COILED          268..296
FT                   /evidence="ECO:0000255"
FT   MOTIF           304..308
FT                   /note="LxCxE motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   MOTIF           411..415
FT                   /note="VHIID"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT   COMPBIAS        279..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   668 AA;  71163 MW;  92B7431046B2B621 CRC64;
     MPPPPPPPPL TPYCRRCPPP HLPPPPPSSP NHFLLHYLHQ LDHQEAAAAA MVRKRPASDM
     DLPPPRRHVT GDLSDVTAAA AAGVGGSGAP SSASAQLPAL PTQLHQLPPA FQHHAPEVDV
     PAHPAPAAHA QAGGEATAST TAWVDGIIRD IIGSSGGAAV SITQLIHNVR EIIHPCNPGL
     ASLLELRLRS LLAADPAPLP PPPQPQQHAL LHGAPAAAPA GLTLPPPPPL PDKRRHEHPP
     PCQQQQQEEP HPAPQSPKAP TAEETAAAAA AAQAAAAAAA KERKEEQRRK QRDEEGLHLL
     TLLLQCAEAV NADNLDDAHQ TLLEIAELAT PFGTSTQRVA AYFAEAMSAR LVSSCLGLYA
     PLPPGSPAAA RLHGRVAAAF QVFNGISPFV KFSHFTANQA IQEAFEREER VHIIDLDIMQ
     GLQWPGLFHI LASRPGGPPR VRLTGLGASM EALEATGKRL SDFADTLGLP FEFCAVAEKA
     GNVDPEKLGV TRREAVAVHW LHHSLYDVTG SDSNTLWLIQ RLAPKVVTMV EQDLSHSGSF
     LARFVEAIHY YSALFDSLDA SYGEDSPERH VVEQQLLSRE IRNVLAVGGP ARTGDVKFGS
     WREKLAQSGF RAASLAGSAA AQASLLLGMF PSDGYTLVEE NGALKLGWKD LCLLTASAWR
     PIQVPPCR