ID   SCT1A_MOUSE             Reviewed;         192 AA.
AC   Q921W8;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Secreted and transmembrane protein 1A;
DE   Flags: Precursor;
GN   Name=Sectm1a {ECO:0000312|EMBL:AAH10462.1, ECO:0000312|MGI:MGI:2384805};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000312|EMBL:AAH10462.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N {ECO:0000312|EMBL:AAH10462.1};
RC   TISSUE=Mammary gland {ECO:0000312|EMBL:AAH10462.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I
CC       membrane protein {ECO:0000250}. Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SECTM family. {ECO:0000305}.
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DR   EMBL; BC010462; AAH10462.1; -; mRNA.
DR   CCDS; CCDS25766.1; -.
DR   AlphaFoldDB; Q921W8; -.
DR   SMR; Q921W8; -.
DR   STRING; 10090.ENSMUSP00000026162; -.
DR   GlyGen; Q921W8; 4 sites.
DR   PhosphoSitePlus; Q921W8; -.
DR   CPTAC; non-CPTAC-4008; -.
DR   PaxDb; Q921W8; -.
DR   PeptideAtlas; Q921W8; -.
DR   PRIDE; Q921W8; -.
DR   ProteomicsDB; 253427; -.
DR   MGI; MGI:2384805; Sectm1a.
DR   eggNOG; ENOG502TM1B; Eukaryota.
DR   InParanoid; Q921W8; -.
DR   PhylomeDB; Q921W8; -.
DR   ChiTaRS; Sectm1a; mouse.
DR   PRO; PR:Q921W8; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q921W8; protein.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; ISO:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR033231; SECTM1.
DR   PANTHER; PTHR15123; PTHR15123; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Secreted;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..192
FT                   /note="Secreted and transmembrane protein 1A"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000271264"
FT   TOPO_DOM        28..165
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        187..192
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        55
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        84
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        127
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  21438 MW;  13D8989D3F07AE1F CRC64;
     MMTCPSVPAI PTLWLFSILL LVVSLNAQNK SWDNPICTEG ILSVPRGNPA VMTCNISNTF
     TDVTIQLSAN GKDKTIFDKK PQGNFSWRGW ELQVQGGQAQ LVIKDTQDDH TGIYLWQLHG
     RQRCYKNITL NILEPSNEDK VPDTTLFTSF PDHAKSSPIE GKPGTLVGVI TVIFILGVAG
     FITFIYYRHR RS