SCTB_DICDI
ID SCTB_DICDI Reviewed; 184 AA.
AC Q23911; Q54EY6;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Secreted protein B {ECO:0000303|PubMed:27187592};
DE AltName: Full=Protein 29C;
DE Flags: Precursor;
GN Name=29C; Synonyms=sctB {ECO:0000303|PubMed:27187592};
GN ORFNames=DDB_G0291255;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-61.
RC STRAIN=AX3;
RX PubMed=3600646; DOI=10.1128/mcb.7.5.1823-1829.1987;
RA Ayres K., Neuman W., Rowekamp W.G., Chung S.;
RT "Developmental regulation of DNase I-hypersensitive sites in Dictyostelium
RT discoideum.";
RL Mol. Cell. Biol. 7:1823-1829(1987).
RN [3]
RP SUBCELLULAR LOCATION.
RX PubMed=27187592; DOI=10.1371/journal.pone.0154875;
RA Sabra A., Leiba J., Mas L., Louwagie M., Coute Y., Journet A., Cosson P.,
RA Aubry L.;
RT "Pycnosomes: condensed endosomal structures secreted by Dictyostelium
RT amoebae.";
RL PLoS ONE 11:E0154875-E0154875(2016).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27187592}.
CC -!- SIMILARITY: Belongs to the Sct family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA33217.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AAFI02000177; EAL61611.1; -; Genomic_DNA.
DR EMBL; M16346; AAA33217.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_635104.1; XM_630012.1.
DR AlphaFoldDB; Q23911; -.
DR STRING; 44689.DDB0215394; -.
DR PaxDb; Q23911; -.
DR EnsemblProtists; EAL61611; EAL61611; DDB_G0291255.
DR GeneID; 8628051; -.
DR KEGG; ddi:DDB_G0291255; -.
DR dictyBase; DDB_G0291255; 29C.
DR eggNOG; ENOG502RHVE; Eukaryota.
DR HOGENOM; CLU_1470790_0_0_1; -.
DR InParanoid; Q23911; -.
DR OMA; AYHNIDS; -.
DR PhylomeDB; Q23911; -.
DR PRO; PR:Q23911; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..184
FT /note="Secreted protein B"
FT /id="PRO_0000361525"
FT MOTIF 164..166
FT /note="Cell attachment site"
FT /evidence="ECO:0000255"
FT CARBOHYD 129
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 184 AA; 19750 MW; 6FF92B47B4033ED5 CRC64;
MRFILVLVLI LGLVSSSFGI NVDKNEVSQT ELQSARDFSS FAIGFAEGIE ISLTGNLHKC
VAAAESSFSE FSNSFHLIDS GLKHKSLGDA KSGLRDFGIG LVDLVKTYQR CGVGKFISEI
SAISKEVTNE TGIIKLIIHE VIDIFHNSHS LTSDFKSAIS DCGRGDYTGC GVASGKIVGI
LMRQ