ID   SCTG_SALCH              Reviewed;         147 AA.
AC   P37422; Q57KM4;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 2.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=SPI-1 type 3 secretion system pilotin {ECO:0000305};
DE   AltName: Full=Invasion lipoprotein InvH;
DE   Flags: Precursor;
GN   Name=invH {ECO:0000303|PubMed:8382333};
GN   Synonyms=sctG {ECO:0000250|UniProtKB:P0CL43}; OrderedLocusNames=SCH_2832;
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=SL2824;
RX   PubMed=8382333; DOI=10.1111/j.1365-2958.1993.tb01100.x;
RA   Altmeyer R.M., McNern J.K., Bossio J.C., Rosenshine I., Finlay B.B.,
RA   Galan J.E.;
RT   "Cloning and molecular characterization of a gene involved in Salmonella
RT   adherence and invasion of cultured epithelial cells.";
RL   Mol. Microbiol. 7:89-98(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67;
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA   Lee Y.-S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
CC   -!- FUNCTION: Involved in the synthesis of the type III secretion system
CC       (T3SS), also called injectisome, which is used to inject bacterial
CC       effector proteins into eukaryotic host cells (By similarity). Pilot
CC       protein that is required for the proper localization of the secretin
CC       InvG/SctC in the outer membrane (By similarity). Necessary for
CC       efficient adherence and entry of these organisms into cultured
CC       epithelial cells (PubMed:8382333). {ECO:0000250|UniProtKB:P0CL43,
CC       ECO:0000269|PubMed:8382333}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000250|UniProtKB:P0CL43}; Lipid-anchor {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the InvH family. {ECO:0000305}.
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DR   EMBL; Z17243; CAA78943.1; -; Genomic_DNA.
DR   EMBL; AE017220; AAX66738.1; -; Genomic_DNA.
DR   PIR; S28064; S28064.
DR   RefSeq; WP_000715102.1; NC_006905.1.
DR   AlphaFoldDB; P37422; -.
DR   SMR; P37422; -.
DR   EnsemblBacteria; AAX66738; AAX66738; SCH_2832.
DR   KEGG; sec:SCH_2832; -.
DR   HOGENOM; CLU_123343_0_0_6; -.
DR   OMA; CMSLPYV; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006830; InvH.
DR   Pfam; PF04741; InvH; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal; Virulence.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           16..147
FT                   /note="SPI-1 type 3 secretion system pilotin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT                   /id="PRO_0000021515"
FT   LIPID           16
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           16
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CONFLICT        36
FT                   /note="Q -> E (in Ref. 1; CAA78943)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   147 AA;  16462 MW;  9358B146D32681B2 CRC64;
     MKKFYSCLPV FLLIGCAQVP LPSSVSKPVQ QPGAQQEQLA NANSIDECQS LPYVPSDLAK
     NKSLSNQNAD NSASKNSAIS SSIFCEKYKQ TKEQALTFFQ EHPQYMRSKE DEEQLMTEFK
     KVLLEPGSKN LSIYQTLLSA HERLQAL