ABDA_APIME
ID ABDA_APIME Reviewed; 74 AA.
AC P15856;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Homeobox protein abdominal-A homolog;
DE AltName: Full=H15;
DE Flags: Fragment;
GN Name=ABD-A;
OS Apis mellifera (Honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Apidae;
OC Apis.
OX NCBI_TaxID=7460;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2574865; DOI=10.1073/pnas.86.24.9971;
RA Walldorf U., Fleig R., Gehring W.J.;
RT "Comparison of homeobox-containing genes of the honeybee and Drosophila.";
RL Proc. Natl. Acad. Sci. U.S.A. 86:9971-9975(1989).
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR EMBL; M29494; AAA27729.1; -; Genomic_DNA.
DR PIR; B34510; B34510.
DR AlphaFoldDB; P15856; -.
DR SMR; P15856; -.
DR STRING; 7460.GB51287-PA; -.
DR PaxDb; P15856; -.
DR PRIDE; P15856; -.
DR eggNOG; KOG0489; Eukaryota.
DR InParanoid; P15856; -.
DR Proteomes; UP000005203; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN <1..>74
FT /note="Homeobox protein abdominal-A homolog"
FT /id="PRO_0000200251"
FT DNA_BIND 8..67
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT NON_TER 1
FT NON_TER 74
SQ SEQUENCE 74 AA; 9195 MW; AB56606C3D7013CD CRC64;
PGPNGCPRRR GRQTYTRFQT LELEKEFHYN HYLTRRRRIE IAHALCLTER QIKIWFQNRR
MKLKKELRAV KEIN