ID   SCVA_COXBU              Reviewed;          30 AA.
AC   Q45966;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Protein ScvA;
DE   AltName: Full=Small-cell-variant protein A;
DE            Short=SCV protein A;
GN   Name=scvA; OrderedLocusNames=CBU_1267.1;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-25, AND POSSIBLE
RP   ROLE IN DNA-BINDING.
RC   STRAIN=Nine Mile phase I, and Nine Mile phase II;
RX   PubMed=8899704; DOI=10.1111/j.1365-2958.1996.tb02651.x;
RA   Heinzen R.A., Howe D., Mallavia L.P., Rockey D.D., Hackstadt T.;
RT   "Developmentally regulated synthesis of an unusually small, basic peptide
RT   by Coxiella burnetii.";
RL   Mol. Microbiol. 22:9-19(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN   [3]
RP   DEVELOPMENTAL STAGE.
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=11447163; DOI=10.1128/iai.69.8.4874-4883.2001;
RA   Seshadri R., Samuel J.E.;
RT   "Characterization of a stress-induced alternate sigma factor, RpoS, of
RT   Coxiella burnetii and its expression during the development cycle.";
RL   Infect. Immun. 69:4874-4883(2001).
CC   -!- FUNCTION: Might be involved in DNA-binding; the protein binds DNA in
CC       gel-shift assays and immunogold electron microscopy shows labelling of
CC       condensed chromatin.
CC   -!- DEVELOPMENTAL STAGE: Only detected in the small cell variant (SCV)
CC       stage (at protein level). LCVs are more metabolically active than SCVs.
CC       The protein is present in SCVs from Nine Mile phase I strains, but its
CC       distribution in phase II strains was not examined (PubMed:8899704).
CC       {ECO:0000269|PubMed:11447163, ECO:0000269|PubMed:8899704}.
CC   -!- MISCELLANEOUS: The protein sequence was determined from Nine Mile phase
CC       II cells.
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DR   EMBL; L49019; AAB39278.1; -; Genomic_DNA.
DR   EMBL; AE016828; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S72626; S72626.
DR   RefSeq; WP_010958114.1; NZ_CDBG01000001.1.
DR   RefSeq; YP_002332993.1; NC_002971.3.
DR   AlphaFoldDB; Q45966; -.
DR   STRING; 227377.CBU_1267a; -.
DR   GeneID; 7065864; -.
DR   KEGG; cbu:CBU_1267a; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; DNA-binding; Reference proteome.
FT   CHAIN           1..30
FT                   /note="Protein ScvA"
FT                   /id="PRO_0000318559"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   30 AA;  3614 MW;  44D6BBBCA242FC04 CRC64;
     MERQNVQQQR GKDQRPQRPG ASNPRRPNQR