ID   SCX4_TITBA              Reviewed;          19 AA.
AC   P56610;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Toxin Tb4;
DE   AltName: Full=TbTx-VI;
DE   AltName: Full=TbTx6;
DE   Flags: Fragment;
OS   Tityus bahiensis (Brazilian scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Tityus.
OX   NCBI_TaxID=50343;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Venom;
RX   PubMed=8611151; DOI=10.1042/bj3130753;
RA   Becerril B., Corona M., Coronas F.I., Zamudio F.Z., Calderon-Aranda E.S.,
RA   Fletcher P.L. Jr., Martin B.M., Possani L.D.;
RT   "Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions
RT   Tityus bahiensis and Tityus stigmurus.";
RL   Biochem. J. 313:753-760(1996).
CC   -!- FUNCTION: Not toxic to mice.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- DOMAIN: Has the structural arrangement of an alpha-helix connected to
CC       antiparallel beta-sheets by disulfide bonds (CS-alpha/beta).
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the long (4 C-C) scorpion toxin superfamily.
CC       Sodium channel inhibitor family. Alpha subfamily. {ECO:0000305}.
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DR   PIR; S62864; S62864.
DR   AlphaFoldDB; P56610; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008200; F:ion channel inhibitor activity; IEA:InterPro.
DR   InterPro; IPR044062; LCN-type_CS_alpha_beta_dom.
DR   PROSITE; PS51863; LCN_CSAB; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted.
FT   CHAIN           1..>19
FT                   /note="Toxin Tb4"
FT                   /id="PRO_0000066795"
FT   DOMAIN          2..>19
FT                   /note="LCN-type CS-alpha/beta"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01210"
FT   NON_TER         19
SQ   SEQUENCE   19 AA;  2151 MW;  3535A2F1E5E67D14 CRC64;
     GKEGYPTDKR GCKLTCFFT