ID   SCXMT_PARLS             Reviewed;          17 AA.
AC   P0C5J6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=Mammal toxin PlMT;
DE   Flags: Fragment;
OS   Parabuthus liosoma (African black tail scorpion) (Parabuthus leiosoma).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Parabuthus.
OX   NCBI_TaxID=470425;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, AND MASS SPECTROMETRY.
RC   TISSUE=Venom;
RX   PubMed=17618664; DOI=10.1016/j.toxicon.2007.04.020;
RA   Ochola J.B., Lwande W., Thiong'o T., Rogo L., Herrmann R., Schepers E.,
RA   Bagine R., Mungai P., Ndiege I.O.;
RT   "Identification of insect-selective and mammal-selective toxins from
RT   Parabuthus leiosoma venom.";
RL   Toxicon 50:449-456(2007).
CC   -!- FUNCTION: Binds to sodium channels and affects the channel activation
CC       process (By similarity). Has high toxic effect on mice but no effect on
CC       B.fusca and C.partellus larvae. {ECO:0000250,
CC       ECO:0000269|PubMed:17618664}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- MASS SPECTROMETRY: Mass=7145.5; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:17618664};
CC   -!- SIMILARITY: Belongs to the long (3 C-C) scorpion toxin superfamily.
CC       Sodium channel inhibitor family. {ECO:0000305}.
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DR   AlphaFoldDB; P0C5J6; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0099106; F:ion channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ion channel impairing toxin; Neurotoxin;
KW   Secreted; Toxin.
FT   CHAIN           1..>17
FT                   /note="Mammal toxin PlMT"
FT                   /id="PRO_0000307896"
FT   NON_TER         17
SQ   SEQUENCE   17 AA;  1956 MW;  97B56A25E9AA11E0 CRC64;
     ADVPGNYPLD KNGNRYY