ID   SDA1_BOVIN              Reviewed;         688 AA.
AC   A5D7C2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Protein SDA1 homolog;
DE   AltName: Full=SDA1 domain-containing protein 1;
GN   Name=SDAD1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hippocampus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000305}.
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DR   EMBL; BC140502; AAI40503.1; -; mRNA.
DR   RefSeq; NP_001095959.1; NM_001102489.1.
DR   AlphaFoldDB; A5D7C2; -.
DR   SMR; A5D7C2; -.
DR   STRING; 9913.ENSBTAP00000007240; -.
DR   PaxDb; A5D7C2; -.
DR   PRIDE; A5D7C2; -.
DR   GeneID; 507675; -.
DR   KEGG; bta:507675; -.
DR   CTD; 55153; -.
DR   eggNOG; KOG2229; Eukaryota.
DR   InParanoid; A5D7C2; -.
DR   OrthoDB; 426305at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR007949; SDA1_dom.
DR   InterPro; IPR012977; Uncharacterised_NUC130/133_N.
DR   PANTHER; PTHR12730; PTHR12730; 1.
DR   Pfam; PF08158; NUC130_3NT; 1.
DR   Pfam; PF05285; SDA1; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Phosphoprotein; Protein transport;
KW   Reference proteome; Ribosome biogenesis; Transport.
FT   CHAIN           1..688
FT                   /note="Protein SDA1 homolog"
FT                   /id="PRO_0000328430"
FT   REGION          484..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          605..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          254..318
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        484..509
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        510..524
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        605..633
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         232
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVU7"
FT   MOD_RES         234
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVU7"
FT   MOD_RES         236
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVU7"
FT   MOD_RES         586
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVU7"
FT   MOD_RES         596
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVU7"
SQ   SEQUENCE   688 AA;  79813 MW;  B419E955D34DCB9E CRC64;
     MSSRNNNKLP SNLPQLQNLI KRDPPAYVEE FLQQYNHYKS NVEIFKLQPN KPSKELAELV
     MFMAQISHCY PEHLSNFPQE LKDLLSYNHT VLDPDLRMTF CKALILLRNK NLINPSSLLE
     LFFELLRCHD KLLRKTLYTH IVTDIKNINA KHKNNKVNIV LQNFMYTMLR DSNATAAKIS
     LDVMIELYRR NIWNDAKTVN VITTACFSKV TKILVAALTF FLGKDEEEKQ DSDSESEDEG
     PTARDLLVQY ATGKKSSKNK KKLEKAMKVL TKHKKKKKPE VFNFSAIHLI HDPQDFAEKL
     LKQLESSKER FEVKMMLMNL ISRLVGIHEL FLFNFYPFVQ RFLQPHQREV TKILLFAAQA
     SHHLVPPEII QSLLMTVANN FVTDKNSGEV MTVGINAIKE ITARCPLAMT EELLQDLAQY
     KTHKDKNVMM SARTLIQLFR TLNPQMLQKK FRGKPTEASI EARVQEYGEL DAKDYIPGAE
     ILEVENEEEN AEGDEDGWES ASLSDEADSD GEWVDVHHSS DEEQKEISEK LNSMPLEERK
     AKAAAVSTSR VLSQEDFQKI RMAQMRKELD AAPGKAQKRK YIEIDSDEER RGELLSLRDI
     ERLHKKPKSD KETRLATAMA GKTDRKEFVR KKTKMNPFSS STNKEKKKQK NFMMMRYSHN
     VRSKNKRSFR EKQLALRDAL LKKRKRMK