ID   SDA1_NEMVE              Reviewed;         687 AA.
AC   A7S6A5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Protein SDA1 homolog;
DE   AltName: Full=SDA1 domain-containing protein 1 homolog;
GN   Name=sdad1; ORFNames=v1g106150;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000305}.
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DR   EMBL; DS469586; EDO40827.1; -; Genomic_DNA.
DR   RefSeq; XP_001632890.1; XM_001632840.1.
DR   AlphaFoldDB; A7S6A5; -.
DR   SMR; A7S6A5; -.
DR   STRING; 45351.EDO40827; -.
DR   EnsemblMetazoa; EDO40827; EDO40827; NEMVEDRAFT_v1g106150.
DR   eggNOG; KOG2229; Eukaryota.
DR   HOGENOM; CLU_009161_3_1_1; -.
DR   InParanoid; A7S6A5; -.
DR   OMA; AMYKTYK; -.
DR   OrthoDB; 426305at2759; -.
DR   PhylomeDB; A7S6A5; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR007949; SDA1_dom.
DR   InterPro; IPR012977; Uncharacterised_NUC130/133_N.
DR   PANTHER; PTHR12730; PTHR12730; 1.
DR   Pfam; PF08158; NUC130_3NT; 1.
DR   Pfam; PF05285; SDA1; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Protein transport; Reference proteome; Ribosome biogenesis;
KW   Transport.
FT   CHAIN           1..687
FT                   /note="Protein SDA1 homolog"
FT                   /id="PRO_0000328432"
FT   REGION          517..549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          561..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          615..687
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..533
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..549
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..584
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        615..647
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        648..665
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        666..680
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   687 AA;  78996 MW;  7981109387C477FD CRC64;
     MKERKSSKMP NNLPQLQNLI KRDSDSLIHT CFALSQFLQQ LRHYQSNLQI FKLNPSHTSK
     VLQELVMFLC QVAHCYPGHL GSLPQELKDL LHKHHSVMDS DLRMTLCRAL ILLRNKDLIS
     PTSILELFFE LFRCNDKVLR QVLYTHIVTD IKNMNAKHKN NKVNSTLQNF MYTMLKDSNA
     VAAKKSLDVL IELYKRNVWK DAKTVNVITT ACFSPVPKIL VAALKFFLGS DEGSAGDDSD
     SESDVSYLKF EFLEMIMNSL ASLLLPKHKK KHKQTSVNFS ALHLINDPQG FSERLFKQLE
     ASTGRFEVRI MLMNLISRLI GVHQLFVFNF YPFLQRYLQP HQREVTKLLM FFSQASHDLV
     PPEVVEPGVR TIVNNFVTER NSHEVMAVGL NAVREVCQRC PLVMTDTLLQ DLAQYKTSKD
     KSVMMASQSL IQLFRSVNPN LLHKKDRGQP TESREDSKPL DYAAVEAKDY IPGAELINYA
     NSTIILLYAT LIPDGWETDE GCDDGSDEDG WIDVQHSSDE EQEDEDPSGE NQEGEEDGQT
     RAARISQMRI LTDEDFKKIR MKQLTKEVQP KLGKKRKRAT TTEEPQGSRN ELVALENIEG
     IYKKRKHDKA SRLETVIAGR QDRPKYGTKK KAKMNEHAGT SNKEKRRKKN FMMMRHNKLV
     RGKTKRSFRD KQIALRDSLL KRKKSKI