ID   SDA1_XENTR              Reviewed;         689 AA.
AC   A4IIB1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein SDA1 homolog;
DE   AltName: Full=SDA1 domain-containing protein 1;
GN   Name=sdad1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000305}.
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DR   EMBL; BC135943; AAI35944.1; -; mRNA.
DR   RefSeq; NP_001095942.1; NM_001102472.1.
DR   AlphaFoldDB; A4IIB1; -.
DR   SMR; A4IIB1; -.
DR   STRING; 8364.ENSXETP00000045076; -.
DR   GeneID; 100124509; -.
DR   KEGG; xtr:100124509; -.
DR   CTD; 55153; -.
DR   eggNOG; KOG2229; Eukaryota.
DR   InParanoid; A4IIB1; -.
DR   OrthoDB; 426305at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR007949; SDA1_dom.
DR   InterPro; IPR012977; Uncharacterised_NUC130/133_N.
DR   PANTHER; PTHR12730; PTHR12730; 1.
DR   Pfam; PF08158; NUC130_3NT; 1.
DR   Pfam; PF05285; SDA1; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Protein transport; Reference proteome;
KW   Ribosome biogenesis; Transport.
FT   CHAIN           1..689
FT                   /note="Protein SDA1 homolog"
FT                   /id="PRO_0000328431"
FT   REGION          485..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..689
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          254..319
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        486..509
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..652
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..681
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  80052 MW;  2F30C811DC250376 CRC64;
     MSGRNNNKLP TNLPQLQNLI KRDPTSYREE FLQQYKHYLS VIEIFKLQPD KPNKELSTLV
     MFMAQTAHCF PQYLEDFPEQ LKSLLRVHHT VMDPDQRMTL CKALILLRNK NLISPSVLLE
     LFFELLRCQD KLLRKTLYTH IVTDIKNINA KHKNNKVNTT LQNFMYTMVR DNNAIAAKIS
     LDVMIELYRR NIWNDAKTVN VISTSCFSKV TKILVAALKF FLGKDEEEKK DSDSESEDEG
     PTARDLMVRY STGKKNTKNK KKLEKAMKVL KKHKKKKRPE VFNFSAIHLV HDPQEFAEKL
     LKQLEASKER FEVKLMHMDL ISRLVGIHEL FLFNFYPFVQ RFLQPHQREV TKILLYAAQA
     THHLVPPEIS QSVLRTIANN FVTDRNSGEV MTVGINAIKE LTARCPLAMT EELLQDLALY
     KTHKDKNVSM SARSLIQLFR SLNPEMLQKK FRGKPTEASK EARIHAYGEL DAKDYIPGAE
     VLEVEQEKTE EPEEDDGWES ASLSDDDEDG EWIDVHHSSD EEQQEVADKI QAMPAEERKA
     KAATVSASRL LSQEDFKKIR LAQLAKEMNN APGKSVKRKN IEIDSDEEER SGELLSLRDI
     EHLHKKPKSD KETRLATVMA GRTDRKEFVR KKSKMNPHAS STNKEKKKNK NFMMMRYSQN
     IRSKNKRSFR DKQIALRDSL LKKRKRLMK