ID   SDC2B_XENLA             Reviewed;         190 AA.
AC   Q6GR51;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Syndecan-2-B;
DE            Short=SYND2-B;
DE   AltName: Full=Xsyn-2;
DE   Flags: Precursor;
GN   Name=sdc2-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8951790; DOI=10.1016/0925-4773(96)00584-9;
RA   Teel A.L., Yost H.J.;
RT   "Embryonic expression patterns of Xenopus syndecans.";
RL   Mech. Dev. 59:115-127(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cell surface proteoglycan that bears heparan sulfate.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
CC   -!- SIMILARITY: Belongs to the syndecan proteoglycan family. {ECO:0000305}.
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DR   EMBL; U41760; AAB81325.1; -; mRNA.
DR   EMBL; BC071080; AAH71080.1; -; mRNA.
DR   RefSeq; NP_001080940.1; NM_001087471.1.
DR   AlphaFoldDB; Q6GR51; -.
DR   SMR; Q6GR51; -.
DR   DNASU; 394283; -.
DR   GeneID; 394283; -.
DR   KEGG; xla:394283; -.
DR   CTD; 394283; -.
DR   Xenbase; XB-GENE-6254666; sdc2.S.
DR   OMA; PREMPRK; -.
DR   OrthoDB; 1362808at2759; -.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 394283; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003585; Neurexin-like.
DR   InterPro; IPR001050; Syndecan.
DR   InterPro; IPR031201; Syndecan-2.
DR   InterPro; IPR027789; Syndecan/Neurexin_dom.
DR   InterPro; IPR030479; Syndecan_CS.
DR   PANTHER; PTHR10915; PTHR10915; 1.
DR   PANTHER; PTHR10915:SF6; PTHR10915:SF6; 1.
DR   Pfam; PF01034; Syndecan; 1.
DR   SMART; SM00294; 4.1m; 1.
DR   PROSITE; PS00964; SYNDECAN; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Heparan sulfate; Membrane; Proteoglycan; Reference proteome;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..190
FT                   /note="Syndecan-2-B"
FT                   /id="PRO_0000259658"
FT   TOPO_DOM        23..136
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..190
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          34..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        36
FT                   /note="O-linked (Xyl...) (glycosaminoglycan) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        48
FT                   /note="O-linked (Xyl...) (glycosaminoglycan) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        50
FT                   /note="O-linked (Xyl...) (glycosaminoglycan) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        52
FT                   /note="O-linked (Xyl...) (glycosaminoglycan) serine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   190 AA;  20902 MW;  8AD7B279A28BF184 CRC64;
     MRNVWLIVPF ALLAAFSGET WAQADRDLYI DSTESSGNYP VDDDDYSSGS GSGIPAHDDD
     EDNVVLTTVQ TLISSPSSEM PYVDTTTLKT QTKMAPETKE PGEVESTNTV LVHENKNIIQ
     TATHTENLFH RTEVLAAVIA GGGIGFLFAV FLILLLVYRM RKKDEGSYDL GERKPSSAVY
     QKAPTKEFYA