SDH5_ARATH
ID SDH5_ARATH Reviewed; 257 AA.
AC Q9SX77;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Succinate dehydrogenase subunit 5, mitochondrial {ECO:0000305};
DE Flags: Precursor;
GN Name=SDH5 {ECO:0000305}; OrderedLocusNames=At1g47420; ORFNames=F16N3.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000305, ECO:0000312|EMBL:AAM60959.1}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP PROTEIN SEQUENCE OF 90-101; 150-165 AND 240-256, AND SUBCELLULAR LOCATION.
RC TISSUE=Leaf, and Stem;
RX PubMed=11743114; DOI=10.1104/pp.010474;
RA Kruft V., Eubel H., Jaensch L., Werhahn W., Braun H.-P.;
RT "Proteomic approach to identify novel mitochondrial proteins in
RT Arabidopsis.";
RL Plant Physiol. 127:1694-1710(2001).
RN [6]
RP PROTEIN SEQUENCE OF 90-109, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=12970493; DOI=10.1104/pp.103.024620;
RA Eubel H., Jansch L., Braun H.P.;
RT "New insights into the respiratory chain of plant mitochondria.
RT Supercomplexes and a unique composition of complex II.";
RL Plant Physiol. 133:274-286(2003).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14671022; DOI=10.1105/tpc.016055;
RA Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J.,
RA Millar A.H.;
RT "Experimental analysis of the Arabidopsis mitochondrial proteome highlights
RT signaling and regulatory components, provides assessment of targeting
RT prediction programs, and indicates plant-specific mitochondrial proteins.";
RL Plant Cell 16:241-256(2004).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RX PubMed=15604729; DOI=10.1007/s11103-004-2316-2;
RA Millar A.H., Eubel H., Jansch L., Kruft V., Heazlewood J.L., Braun H.P.;
RT "Mitochondrial cytochrome c oxidase and succinate dehydrogenase complexes
RT contain plant specific subunits.";
RL Plant Mol. Biol. 56:77-90(2004).
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000305}.
CC -!- SUBUNIT: Component of complex II composed of eight subunits in plants:
CC four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein
CC (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a
CC large and a small subunit.), as well as four subunits unknown in
CC mitochondria from bacteria and heterotrophic eukaryotes.
CC {ECO:0000269|PubMed:15604729}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000269|PubMed:11743114, ECO:0000269|PubMed:14671022}; Peripheral
CC membrane protein {ECO:0000305}.
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DR EMBL; AC007519; AAD46040.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32168.1; -; Genomic_DNA.
DR EMBL; AF344326; AAK06877.1; -; mRNA.
DR EMBL; AY054563; AAK96754.1; -; mRNA.
DR EMBL; AY034947; AAK59453.1; -; mRNA.
DR EMBL; AY062990; AAL34164.1; -; mRNA.
DR EMBL; BT000345; AAN15664.1; -; mRNA.
DR EMBL; AY084381; AAM60959.1; -; mRNA.
DR PIR; H96514; H96514.
DR RefSeq; NP_564506.1; NM_103636.3.
DR AlphaFoldDB; Q9SX77; -.
DR SMR; Q9SX77; -.
DR BioGRID; 26372; 8.
DR IntAct; Q9SX77; 1.
DR STRING; 3702.AT1G47420.1; -.
DR iPTMnet; Q9SX77; -.
DR MetOSite; Q9SX77; -.
DR SwissPalm; Q9SX77; -.
DR PaxDb; Q9SX77; -.
DR PRIDE; Q9SX77; -.
DR ProteomicsDB; 232873; -.
DR EnsemblPlants; AT1G47420.1; AT1G47420.1; AT1G47420.
DR GeneID; 841147; -.
DR Gramene; AT1G47420.1; AT1G47420.1; AT1G47420.
DR KEGG; ath:AT1G47420; -.
DR Araport; AT1G47420; -.
DR TAIR; locus:2015428; AT1G47420.
DR eggNOG; ENOG502QQK1; Eukaryota.
DR HOGENOM; CLU_076459_0_0_1; -.
DR InParanoid; Q9SX77; -.
DR OMA; PDENYLR; -.
DR OrthoDB; 1220352at2759; -.
DR PhylomeDB; Q9SX77; -.
DR BioCyc; ARA:AT1G47420-MON; -.
DR BioCyc; MetaCyc:AT1G47420-MON; -.
DR UniPathway; UPA00223; -.
DR PRO; PR:Q9SX77; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SX77; baseline and differential.
DR Genevisible; Q9SX77; AT.
DR GO; GO:0005749; C:mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone); IDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0045273; C:respiratory chain complex II; IDA:UniProtKB.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR InterPro; IPR025397; SDH5.
DR PANTHER; PTHR36139; PTHR36139; 1.
DR Pfam; PF14290; DUF4370; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Transit peptide;
KW Tricarboxylic acid cycle.
FT TRANSIT 1..89
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:11743114,
FT ECO:0000269|PubMed:12970493"
FT CHAIN 90..257
FT /note="Succinate dehydrogenase subunit 5, mitochondrial"
FT /evidence="ECO:0000269|PubMed:11743114,
FT ECO:0000269|PubMed:12970493"
FT /id="PRO_0000013632"
SQ SEQUENCE 257 AA; 28106 MW; 315C88C2C3CC1DE9 CRC64;
MGTLGRAIHT VGNRIRGTAQ AQARVGSLLQ GSHHIEKHLS RHRTLITVAP NASVIGDVQI
NKGSFISYAS VSRDLQYPRA MGMGQVRRFS EDVSHMPEME DSDVLNAFKD LMAADWAELP
SAVVKDAKTA ISKNTDDKAG QEALKNVFRA AEAVEEFGGI LTSIKMEIDD SIGMSGEGVK
PLPNDITDAL RTAYQRYAEY LDSFEPEEVY LKKKVEMELG TKMIHLKMRC SGLGSEWGKV
TVLGTSGLSG SYVEQRA
