ID   ABDA_SCHGR              Reviewed;         157 AA.
AC   P29556;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Homeobox protein abdominal-A homolog;
DE   Flags: Fragment;
GN   Name=ABD-A;
OS   Schistocerca gregaria (Desert locust) (Gryllus gregarius).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Cyrtacanthacridinae; Schistocerca.
OX   NCBI_TaxID=7010;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1982432; DOI=10.1242/dev.110.3.915;
RA   Tear G., Akam M., Martinez-Arias A.;
RT   "Isolation of an abdominal-A gene from the locust Schistocerca gregaria and
RT   its expression during early embryogenesis.";
RL   Development 110:915-925(1990).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR   EMBL; X54674; CAA38485.1; -; Genomic_DNA.
DR   PIR; S13803; S13803.
DR   AlphaFoldDB; P29556; -.
DR   SMR; P29556; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR022132; Abdominal-A.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF12407; Abdominal-A; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus.
FT   CHAIN           <1..157
FT                   /note="Homeobox protein abdominal-A homolog"
FT                   /id="PRO_0000200253"
FT   DNA_BIND        6..65
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          73..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..125
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   157 AA;  19076 MW;  036DBD00D6C69214 CRC64;
     PNGCPRRRGR QTYTRFQTLE LEKEFHFNHY LTRRRRIEIA HALCLTERQI KIWFQNRRMK
     LKKELRAVKE INEQARRERE EQDRLKQQQE KKLEQQQQQQ QQQQQQQQQQ QQQQAPPQQP
     PQQHHTISHH LHDQHKLGLE KAPPGADLLK AVAKVPT