ID   BEX2_BOVIN              Reviewed;         128 AA.
AC   Q2TBV0;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Protein BEX2;
DE   AltName: Full=Brain-expressed X-linked protein 2 homolog;
GN   Name=BEX2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of mitochondrial apoptosis and G1 cell cycle.
CC       Regulates the level of PP2A regulatory subunit B and PP2A phosphatase
CC       activity (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with OMP. Interacts with LMO2, possibly leading to
CC       regulate the transcriptional activity of a DNA-binding complex
CC       containing LMO2 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BEX family. {ECO:0000305}.
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DR   EMBL; BC109609; AAI09610.1; -; mRNA.
DR   RefSeq; NP_001070502.1; NM_001077034.1.
DR   RefSeq; XP_005227814.1; XM_005227757.3.
DR   AlphaFoldDB; Q2TBV0; -.
DR   STRING; 9913.ENSBTAP00000043951; -.
DR   PaxDb; Q2TBV0; -.
DR   Ensembl; ENSBTAT00000046677; ENSBTAP00000043951; ENSBTAG00000032875.
DR   GeneID; 767968; -.
DR   KEGG; bta:767968; -.
DR   CTD; 84707; -.
DR   VEuPathDB; HostDB:ENSBTAG00000032875; -.
DR   eggNOG; ENOG502RW3Y; Eukaryota.
DR   GeneTree; ENSGT00940000153412; -.
DR   HOGENOM; CLU_123122_1_0_1; -.
DR   InParanoid; Q2TBV0; -.
DR   OMA; AKCPGGA; -.
DR   OrthoDB; 1532209at2759; -.
DR   TreeFam; TF337909; -.
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000032875; Expressed in adenohypophysis and 73 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR007623; BEX.
DR   InterPro; IPR021156; TF_A-like/BEX.
DR   PANTHER; PTHR19430; PTHR19430; 1.
DR   Pfam; PF04538; BEX; 1.
DR   PIRSF; PIRSF008633; BEX; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Cell cycle; Cytoplasm; Methylation; Nucleus; Reference proteome.
FT   CHAIN           1..128
FT                   /note="Protein BEX2"
FT                   /id="PRO_0000229776"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          103..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         50
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9WTZ8"
SQ   SEQUENCE   128 AA;  15236 MW;  9BC747F562E84711 CRC64;
     MMPKEEQVLK NLTMENANEE NEKKDEKEQD ANKGEPLALS LGAGEYCVPR GNRRRFRVRQ
     PILHYRWDMT QRLGKPQARM REENIERIGE EMRQLMEKLR EKQLSHSLRA VSTDPPHHEH
     NDEFCLMP