位置:首页 > 蛋白库 > SDHD_BURP1
SDHD_BURP1
ID   SDHD_BURP1              Reviewed;         445 AA.
AC   Q3JJ76;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Probable D-serine dehydratase {ECO:0000255|HAMAP-Rule:MF_01030};
DE            EC=4.3.1.18 {ECO:0000255|HAMAP-Rule:MF_01030};
DE   AltName: Full=D-serine deaminase {ECO:0000255|HAMAP-Rule:MF_01030};
DE            Short=DSD {ECO:0000255|HAMAP-Rule:MF_01030};
GN   Name=dsdA {ECO:0000255|HAMAP-Rule:MF_01030};
GN   OrderedLocusNames=BURPS1710b_A1220;
OS   Burkholderia pseudomallei (strain 1710b).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=320372;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1710b;
RX   PubMed=20333227; DOI=10.1093/gbe/evq003;
RA   Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA   Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA   Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA   Nierman W.C.;
RT   "Continuing evolution of Burkholderia mallei through genome reduction and
RT   large-scale rearrangements.";
RL   Genome Biol. Evol. 2:102-116(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-serine = NH4(+) + pyruvate; Xref=Rhea:RHEA:13977,
CC         ChEBI:CHEBI:15361, ChEBI:CHEBI:28938, ChEBI:CHEBI:35247; EC=4.3.1.18;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01030};
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01030};
CC   -!- SIMILARITY: Belongs to the serine/threonine dehydratase family. DsdA
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01030}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000125; ABA52188.1; -; Genomic_DNA.
DR   RefSeq; WP_004529338.1; NC_007435.1.
DR   AlphaFoldDB; Q3JJ76; -.
DR   SMR; Q3JJ76; -.
DR   EnsemblBacteria; ABA52188; ABA52188; BURPS1710b_A1220.
DR   KEGG; bpm:BURPS1710b_A1220; -.
DR   HOGENOM; CLU_035707_0_0_4; -.
DR   OMA; ESDPNCF; -.
DR   OrthoDB; 912282at2; -.
DR   Proteomes; UP000002700; Chromosome II.
DR   GO; GO:0008721; F:D-serine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0046416; P:D-amino acid metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   HAMAP; MF_01030; D_Ser_dehydrat; 1.
DR   InterPro; IPR011780; D_Ser_am_lyase.
DR   InterPro; IPR001926; PLP-dep.
DR   InterPro; IPR036052; Trypto_synt_PLP_dependent.
DR   PANTHER; PTHR48078:SF9; PTHR48078:SF9; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; SSF53686; 1.
DR   TIGRFAMs; TIGR02035; D_Ser_am_lyase; 1.
PE   3: Inferred from homology;
KW   Lyase; Pyridoxal phosphate.
FT   CHAIN           1..445
FT                   /note="Probable D-serine dehydratase"
FT                   /id="PRO_0000291720"
FT   MOD_RES         111
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01030"
SQ   SEQUENCE   445 AA;  46292 MW;  F4E22B08A8B6EAD6 CRC64;
     MPVGRSLSLD PNLLAQLQSH SPTLWLNPHQ GMPLPDFAPT AADLADADAR LRRCAGLLAE
     LFAELRPSGG LIASPLQPAE PLKRAARAGH AQAGAWYVKR DDALPVAGSI KARGGFHEVL
     ALAESIAERH GLAGADTDRR ALASGAARAR FARHTVMVGS TGNLGLSIGM LASALGFRTV
     AHMSADAKAW KKARLRTRGV EVVEHAGDYA KAVDAGRRQA AGMPCCHFVD DEGSRMLFLG
     YATAAAELAA QLAQAGRPVD ARHPLFVHLP CGVGGAPGGI VYGLKALYGE HVHAFVAEPT
     ASPCVLVQLA GDAAHPRSVY DIGLDNRTEA DGLAVAQASP LAAALLRAQA AGAFTVDDRQ
     LFAHLLDARE RLGIDLEPSA AAAFGGPAWI AGSDAGRAYL RGRGIDPDAA THVIWATGGS
     LVPAQEHRRF QAHARAQRQV GGAGA
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024