SDHE_ACIAD
ID SDHE_ACIAD Reviewed; 85 AA.
AC Q6F7U1;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=FAD assembly factor SdhE;
GN Name=sdhE; OrderedLocusNames=ACIAD3189;
OS Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=62977;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33305 / BD413 / ADP1;
RX PubMed=15514110; DOI=10.1093/nar/gkh910;
RA Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT a versatile and naturally transformation competent bacterium.";
RL Nucleic Acids Res. 32:5766-5779(2004).
CC -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC attachment of the cofactor into other proteins. Plays an essential role
CC in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC II), an enzyme complex that is a component of both the tricarboxylic
CC acid cycle and the electron transport chain, and which couples the
CC oxidation of succinate to fumarate with the reduction of ubiquinone
CC (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC {ECO:0000305}.
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DR EMBL; CR543861; CAG69874.1; -; Genomic_DNA.
DR RefSeq; WP_004924176.1; NC_005966.1.
DR AlphaFoldDB; Q6F7U1; -.
DR SMR; Q6F7U1; -.
DR STRING; 62977.ACIAD3189; -.
DR EnsemblBacteria; CAG69874; CAG69874; ACIAD3189.
DR GeneID; 45235405; -.
DR KEGG; aci:ACIAD3189; -.
DR eggNOG; COG2938; Bacteria.
DR HOGENOM; CLU_103054_2_0_6; -.
DR OMA; AQMLTHE; -.
DR OrthoDB; 2055100at2; -.
DR BioCyc; ASP62977:ACIAD_RS14450-MON; -.
DR Proteomes; UP000000430; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.150.250; -; 1.
DR InterPro; IPR005631; SDH.
DR InterPro; IPR036714; SDH_sf.
DR Pfam; PF03937; Sdh5; 1.
DR SUPFAM; SSF109910; SSF109910; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..85
FT /note="FAD assembly factor SdhE"
FT /id="PRO_0000214391"
SQ SEQUENCE 85 AA; 10074 MW; B71F12ED4E835EBB CRC64;
MSEELTLEER KVIYRARRGL KEIDVYFDPY VKNYYLTAPA SEKALFAELV AQEDPDLLDW
FMEVSEPPQV ELKQLIQKLK HYVHG