SDHE_HAEDU
ID SDHE_HAEDU Reviewed; 82 AA.
AC Q7VPK3;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=FAD assembly factor SdhE;
GN Name=sdhE; OrderedLocusNames=HD_0065;
OS Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=233412;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=35000HP / ATCC 700724;
RA Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA Nguyen D., Wang J., Forst C., Hood L.;
RT "The complete genome sequence of Haemophilus ducreyi.";
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC attachment of the cofactor into other proteins. Plays an essential role
CC in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC II), an enzyme complex that is a component of both the tricarboxylic
CC acid cycle and the electron transport chain, and which couples the
CC oxidation of succinate to fumarate with the reduction of ubiquinone
CC (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC {ECO:0000305}.
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DR EMBL; AE017143; AAP95077.1; -; Genomic_DNA.
DR RefSeq; WP_010944131.1; NC_002940.2.
DR AlphaFoldDB; Q7VPK3; -.
DR SMR; Q7VPK3; -.
DR STRING; 233412.HD_0065; -.
DR EnsemblBacteria; AAP95077; AAP95077; HD_0065.
DR KEGG; hdu:HD_0065; -.
DR eggNOG; COG2938; Bacteria.
DR HOGENOM; CLU_103054_2_2_6; -.
DR OMA; ADKERYW; -.
DR Proteomes; UP000001022; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.150.250; -; 1.
DR InterPro; IPR005631; SDH.
DR InterPro; IPR036714; SDH_sf.
DR Pfam; PF03937; Sdh5; 1.
DR SUPFAM; SSF109910; SSF109910; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..82
FT /note="FAD assembly factor SdhE"
FT /id="PRO_0000214399"
SQ SEQUENCE 82 AA; 9862 MW; 3432843B65DC37E5 CRC64;
MAELNRFKIE WQCRRGMREL DKMIMPFYQQ YFEQLSEAEQ RTFVTMLSYT DPELFRWVMH
QSPAPTVAIS ALIERIRASI EA