SDHE_PASMU
ID SDHE_PASMU Reviewed; 84 AA.
AC Q9CK44;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=FAD assembly factor SdhE;
GN Name=sdhE; OrderedLocusNames=PM1790;
OS Pasteurella multocida (strain Pm70).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Pasteurella.
OX NCBI_TaxID=272843;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pm70;
RX PubMed=11248100; DOI=10.1073/pnas.051634598;
RA May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT "Complete genomic sequence of Pasteurella multocida Pm70.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC attachment of the cofactor into other proteins. Plays an essential role
CC in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC II), an enzyme complex that is a component of both the tricarboxylic
CC acid cycle and the electron transport chain, and which couples the
CC oxidation of succinate to fumarate with the reduction of ubiquinone
CC (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC {ECO:0000305}.
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DR EMBL; AE004439; AAK03874.1; -; Genomic_DNA.
DR RefSeq; WP_005718978.1; NC_002663.1.
DR AlphaFoldDB; Q9CK44; -.
DR SMR; Q9CK44; -.
DR STRING; 747.DR93_147; -.
DR EnsemblBacteria; AAK03874; AAK03874; PM1790.
DR KEGG; pmu:PM1790; -.
DR HOGENOM; CLU_103054_2_2_6; -.
DR OMA; FEHEYDT; -.
DR Proteomes; UP000000809; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.150.250; -; 1.
DR InterPro; IPR005631; SDH.
DR InterPro; IPR036714; SDH_sf.
DR Pfam; PF03937; Sdh5; 1.
DR SUPFAM; SSF109910; SSF109910; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..84
FT /note="FAD assembly factor SdhE"
FT /id="PRO_0000214408"
SQ SEQUENCE 84 AA; 10159 MW; 85D6A1F9AF7CC8C1 CRC64;
MTQYNKLRIE WDCRRGMLEL DNVIMPFYRQ HFDALSDTQK DTFIRLLACS DLQLFSWFFN
RGMATDPQLQ QMVDYIQKTL KLTD