ID   SDHE_PSEAE              Reviewed;          84 AA.
AC   Q9I5G9;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=FAD assembly factor SdhE;
GN   Name=sdhE; OrderedLocusNames=PA0760;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC       attachment of the cofactor into other proteins. Plays an essential role
CC       in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC       II), an enzyme complex that is a component of both the tricarboxylic
CC       acid cycle and the electron transport chain, and which couples the
CC       oxidation of succinate to fumarate with the reduction of ubiquinone
CC       (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC       attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC       flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC   -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG04149.1; -; Genomic_DNA.
DR   PIR; H83549; H83549.
DR   RefSeq; NP_249451.1; NC_002516.2.
DR   RefSeq; WP_003085532.1; NZ_QZGE01000007.1.
DR   AlphaFoldDB; Q9I5G9; -.
DR   SMR; Q9I5G9; -.
DR   STRING; 287.DR97_1224; -.
DR   PaxDb; Q9I5G9; -.
DR   PRIDE; Q9I5G9; -.
DR   DNASU; 880656; -.
DR   EnsemblBacteria; AAG04149; AAG04149; PA0760.
DR   GeneID; 880656; -.
DR   KEGG; pae:PA0760; -.
DR   PATRIC; fig|208964.12.peg.789; -.
DR   PseudoCAP; PA0760; -.
DR   HOGENOM; CLU_103054_2_2_6; -.
DR   InParanoid; Q9I5G9; -.
DR   OMA; FEHEYDT; -.
DR   PhylomeDB; Q9I5G9; -.
DR   BioCyc; PAER208964:G1FZ6-773-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006105; P:succinate metabolic process; IBA:GO_Central.
DR   Gene3D; 1.10.150.250; -; 1.
DR   InterPro; IPR005631; SDH.
DR   InterPro; IPR036714; SDH_sf.
DR   Pfam; PF03937; Sdh5; 1.
DR   SUPFAM; SSF109910; SSF109910; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..84
FT                   /note="FAD assembly factor SdhE"
FT                   /id="PRO_0000214412"
SQ   SEQUENCE   84 AA;  10147 MW;  964141C4AE8B4082 CRC64;
     MADETELKRL YWHSRRGMLE LDVLLVPFVQ EVYPGLDAED QARFRKLLEC EDQDMFGWFM
     QRGEPEDADL RRMVRMILDR VQPD