ID   BEXC_HAEIF              Reviewed;         377 AA.
AC   P22930;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Capsule polysaccharide export inner-membrane protein BexC;
GN   Name=bexC;
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Eagan / Serotype B;
RX   PubMed=2082145; DOI=10.1111/j.1365-2958.1990.tb02034.x;
RA   Kroll J.S., Loynds B., Brophy L.N., Moxon E.R.;
RT   "The bex locus in encapsulated Haemophilus influenzae: a chromosomal region
RT   involved in capsule polysaccharide export.";
RL   Mol. Microbiol. 4:1853-1862(1990).
CC   -!- FUNCTION: May form an ATP-driven capsule polysaccharide export
CC       apparatus, in association with the BexA, BexB and BexD proteins.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BexC/CtrB/KpsE family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-20 is the initiator.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA38732.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X54987; CAA38731.1; -; Genomic_DNA.
DR   EMBL; X54987; CAA38732.1; ALT_INIT; Genomic_DNA.
DR   PIR; S12233; BWHIXC.
DR   AlphaFoldDB; P22930; -.
DR   SMR; P22930; -.
DR   PRIDE; P22930; -.
DR   GO; GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR   GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005705; BexC_CtrB_KpsE_VexD.
DR   TIGRFAMs; TIGR01010; BexC_CtrB_KpsE; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Cell inner membrane; Cell membrane;
KW   Membrane; Polysaccharide transport; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..377
FT                   /note="Capsule polysaccharide export inner-membrane protein
FT                   BexC"
FT                   /id="PRO_0000064912"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  42292 MW;  86D08C70DEB03FC7 CRC64;
     MTTENAAIPT KKKKSFWKKM KPLFGLTVLI PTAFSAVYFG LFASDIYVSE SSFVVRSPRS
     QSSLSGVGAL LQSTGFSRSQ DDTYSVQEYM RSRTALSALE QGLPLRTFYS EKGDLLSRFN
     GFGLNDTQEA FYRYFKERLS VDVDSISGIA TLRVHAFDAE EGYQINERLL KEGESLINRL
     NERARKDTIE FAEQAVKDAE KNVNETAQAL SQYRIKNKIF DLPAQSGVQL SLISSLKSEL
     IRVETQLAQL VSITPDNPQV PALQMRQKSL KKEIDEQTRQ LSGNGNSAAT QTADYQRLML
     ANELAQQQLA AAMTSLQNTR GEADRQQLYL EVISQPSKPD WALEPSRIYN IIATFIIGLM
     LYGVLNLLIA SIREHKN