ID   SDHE_SALTI              Reviewed;          88 AA.
AC   Q8XEN6; Q7AMC1;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=FAD assembly factor SdhE;
GN   Name=sdhE; Synonyms=ygfY; OrderedLocusNames=STY3203, t2965;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC       attachment of the cofactor into other proteins. Plays an essential role
CC       in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC       II), an enzyme complex that is a component of both the tricarboxylic
CC       acid cycle and the electron transport chain, and which couples the
CC       oxidation of succinate to fumarate with the reduction of ubiquinone
CC       (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC       attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC       flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:P64559}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC   -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC       {ECO:0000305}.
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DR   EMBL; AL513382; CAD02877.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO70517.1; -; Genomic_DNA.
DR   RefSeq; NP_457445.1; NC_003198.1.
DR   RefSeq; WP_000351186.1; NZ_WSUR01000024.1.
DR   AlphaFoldDB; Q8XEN6; -.
DR   SMR; Q8XEN6; -.
DR   STRING; 220341.16504130; -.
DR   EnsemblBacteria; AAO70517; AAO70517; t2965.
DR   GeneID; 66757346; -.
DR   KEGG; stt:t2965; -.
DR   KEGG; sty:STY3203; -.
DR   PATRIC; fig|220341.7.peg.3261; -.
DR   eggNOG; COG2938; Bacteria.
DR   HOGENOM; CLU_103054_2_2_6; -.
DR   OMA; FEHEYDT; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.150.250; -; 1.
DR   InterPro; IPR005631; SDH.
DR   InterPro; IPR036714; SDH_sf.
DR   Pfam; PF03937; Sdh5; 1.
DR   SUPFAM; SSF109910; SSF109910; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm.
FT   CHAIN           1..88
FT                   /note="FAD assembly factor SdhE"
FT                   /id="PRO_0000214421"
SQ   SEQUENCE   88 AA;  10550 MW;  F5160E11E492A073 CRC64;
     MDIHNKARIH WACRRGMREL DISIMPFFEH EYDSLSDEEK RIFVRLLQSD DPDLFNWLMN
     HGKPADAELE QMVRLIQTRN RERGPVAI