SDHE_VIBVU
ID SDHE_VIBVU Reviewed; 86 AA.
AC Q8DC84;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=FAD assembly factor SdhE;
GN Name=sdhE; OrderedLocusNames=VV1_1557;
OS Vibrio vulnificus (strain CMCP6).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=216895;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMCP6;
RA Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: An FAD assembly protein, which accelerates covalent
CC attachment of the cofactor into other proteins. Plays an essential role
CC in the assembly of succinate dehydrogenase (SDH, respiratory complex
CC II), an enzyme complex that is a component of both the tricarboxylic
CC acid cycle and the electron transport chain, and which couples the
CC oxidation of succinate to fumarate with the reduction of ubiquinone
CC (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC attachment of FAD) of the flavoprotein subunit SdhA of SDH and other
CC flavinylated proteins as well. {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:G4V4G2}.
CC -!- SIMILARITY: Belongs to the SdhE FAD assembly factor family.
CC {ECO:0000305}.
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DR EMBL; AE016795; AAO09981.1; -; Genomic_DNA.
DR RefSeq; WP_011079492.1; NC_004459.3.
DR AlphaFoldDB; Q8DC84; -.
DR SMR; Q8DC84; -.
DR EnsemblBacteria; AAO09981; AAO09981; VV1_1557.
DR GeneID; 66966009; -.
DR KEGG; vvu:VV1_1557; -.
DR HOGENOM; CLU_103054_2_2_6; -.
DR OMA; FEHEYDT; -.
DR Proteomes; UP000002275; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.150.250; -; 1.
DR InterPro; IPR005631; SDH.
DR InterPro; IPR036714; SDH_sf.
DR Pfam; PF03937; Sdh5; 1.
DR SUPFAM; SSF109910; SSF109910; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm.
FT CHAIN 1..86
FT /note="FAD assembly factor SdhE"
FT /id="PRO_0000214428"
SQ SEQUENCE 86 AA; 10109 MW; A788001FCE201C80 CRC64;
MYTTEEKARI RWACRRGMLE LDVVVMPFFE ECFEKLSEQE QRDFVSLLEC DDPDLFTWVM
GHGRSENLGH ASMVDKIVAH NLSKVR