ABDH3_CAEEL
ID ABDH3_CAEEL Reviewed; 375 AA.
AC Q18610;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Protein abhd-3.2 {ECO:0000305};
DE EC=3.1.1.-;
GN Name=abhd-3.2 {ECO:0000312|WormBase:C44C1.5a};
GN ORFNames=C44C1.5 {ECO:0000312|WormBase:C44C1.5a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000305}.
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DR EMBL; FO080474; CCD63974.1; -; Genomic_DNA.
DR PIR; T29568; T29568.
DR RefSeq; NP_001024458.1; NM_001029287.3.
DR AlphaFoldDB; Q18610; -.
DR BioGRID; 45403; 1.
DR IntAct; Q18610; 1.
DR STRING; 6239.C44C1.5a.1; -.
DR ESTHER; caeel-yyc5; abh_upf0017.
DR PaxDb; Q18610; -.
DR PeptideAtlas; Q18610; -.
DR EnsemblMetazoa; C44C1.5a.1; C44C1.5a.1; WBGene00016644.
DR GeneID; 180450; -.
DR KEGG; cel:CELE_C44C1.5; -.
DR UCSC; C44C1.5a; c. elegans.
DR CTD; 180450; -.
DR WormBase; C44C1.5a; CE04215; WBGene00016644; abhd-3.2.
DR eggNOG; KOG1838; Eukaryota.
DR GeneTree; ENSGT00950000182902; -.
DR HOGENOM; CLU_032487_4_0_1; -.
DR InParanoid; Q18610; -.
DR OMA; FWFTGYS; -.
DR OrthoDB; 1162019at2759; -.
DR PhylomeDB; Q18610; -.
DR Reactome; R-CEL-1483191; Synthesis of PC.
DR PRO; PR:Q18610; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00016644; Expressed in adult organism and 1 other tissue.
DR ExpressionAtlas; Q18610; baseline and differential.
DR GO; GO:0008126; F:acetylesterase activity; IBA:GO_Central.
DR GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR GO; GO:0034338; F:short-chain carboxylesterase activity; IBA:GO_Central.
DR GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IBA:GO_Central.
DR GO; GO:0051793; P:medium-chain fatty acid catabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR000952; AB_hydrolase_4_CS.
DR InterPro; IPR012020; ABHD4.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
DR PROSITE; PS01133; UPF0017; 1.
PE 3: Inferred from homology;
KW Hydrolase; Reference proteome; Serine esterase.
FT CHAIN 1..375
FT /note="Protein abhd-3.2"
FT /evidence="ECO:0000305"
FT /id="PRO_0000212460"
FT DOMAIN 108..203
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000255"
FT ACT_SITE 189
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 315
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 344
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
SQ SEQUENCE 375 AA; 42337 MW; 4E159E684EFE48B5 CRC64;
MVLPLILTLV IVAPIFLWMY SWYISAIPKH YVKPGTKLQK KVHSNLRILE QKYHPSWWCP
FGTTQTVVRQ IFRDCPSLPF TREIVEFDDG GAAGIDWLIP EGADDTTPIV VFLPGITGST
HDSSYVLHPV KEARDKGWKC VVVNPRGLGG VKLRTTRTYN AATPHDFAFI AKMINERYPD
AKKLGCGFSM GGMILWNYLA MTGENADLDG GMIVSSPWDP LVASDSIECF IPQLIFNSFI
AKNLVDMVRP YRELFKDMVD FDEVCRCNTV RGFDRSFVIP MYGFKSCDDY YRQATLATKV
DKIKIPCVTL NSVDDYFSPV ECIPTLDIME SDYVCGIITN HGGHTAFMES ADPNARGMVE
KLLSQWGNMI FHDYS
