SDO1_SCHPO
ID SDO1_SCHPO Reviewed; 246 AA.
AC O14179;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Ribosome maturation protein sdo1;
GN Name=sdo1; ORFNames=SPAC4F8.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit and
CC translational activation of ribosomes. Together with the EF-2-like
CC GTPase ria1, may trigger the GTP-dependent release of tif6 from 60S
CC pre-ribosomes in the cytoplasm, thereby activating ribosomes for
CC translation competence by allowing 80S ribosome assembly and
CC facilitating tif6 recycling to the nucleus, where it is required for
CC 60S rRNA processing and nuclear export.
CC -!- SUBUNIT: Associates with the 60S ribosomal subunit. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SDO1/SBDS family. {ECO:0000305}.
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DR EMBL; CU329670; CAB11050.1; -; Genomic_DNA.
DR PIR; T38833; T38833.
DR RefSeq; NP_593869.1; NM_001019298.2.
DR AlphaFoldDB; O14179; -.
DR SMR; O14179; -.
DR BioGRID; 279879; 1.
DR STRING; 4896.SPAC4F8.03.1; -.
DR iPTMnet; O14179; -.
DR MaxQB; O14179; -.
DR PaxDb; O14179; -.
DR PRIDE; O14179; -.
DR EnsemblFungi; SPAC4F8.03.1; SPAC4F8.03.1:pep; SPAC4F8.03.
DR GeneID; 2543459; -.
DR KEGG; spo:SPAC4F8.03; -.
DR PomBase; SPAC4F8.03; sdo1.
DR VEuPathDB; FungiDB:SPAC4F8.03; -.
DR eggNOG; KOG2917; Eukaryota.
DR HOGENOM; CLU_043216_1_1_1; -.
DR InParanoid; O14179; -.
DR OMA; AVNPQMD; -.
DR PhylomeDB; O14179; -.
DR PRO; PR:O14179; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0030687; C:preribosome, large subunit precursor; ISO:PomBase.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISO:PomBase.
DR GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; ISO:PomBase.
DR Gene3D; 1.10.10.900; -; 1.
DR Gene3D; 3.30.1250.10; -; 1.
DR InterPro; IPR018023; Ribosome_mat_SBDS_CS.
DR InterPro; IPR036786; Ribosome_mat_SBDS_N_sf.
DR InterPro; IPR018978; Ribosome_mat_Sdo1/SBDS_C.
DR InterPro; IPR019783; Ribosome_mat_Sdo1/SBDS_N.
DR InterPro; IPR002140; Sdo1/SBDS.
DR InterPro; IPR039100; Sdo1/SBDS-like.
DR InterPro; IPR037188; Sdo1/SBDS_central_sf.
DR PANTHER; PTHR10927; PTHR10927; 1.
DR Pfam; PF01172; SBDS; 1.
DR Pfam; PF09377; SBDS_C; 1.
DR SUPFAM; SSF109728; SSF109728; 1.
DR SUPFAM; SSF89895; SSF89895; 1.
DR TIGRFAMs; TIGR00291; RNA_SBDS; 1.
DR PROSITE; PS01267; UPF0023; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..246
FT /note="Ribosome maturation protein sdo1"
FT /id="PRO_0000123765"
SQ SEQUENCE 246 AA; 28075 MW; 57640E154882ED39 CRC64;
MVISQPVGQI RLTNVSVVKY KKGGKRFEVA CYKNKVTEWR NKIETDLDEV LQIHNVFNNV
SKGHVASRQD LKKAFGTDDI DKIILEILQK GDFQVGEKER HHQMSSTYRD IVSHVTAMCM
DPNSKRPYPA SIIEKALSDC GFSVSTSKTA KSQALEAIKK LQEKNEIPIV RARMRIRIVV
DVKQGKALRE RLRSLADEIE EENIDDEYEC IALVIPGNYK LIDELVRNET KNRGMVQVLD
MSEART
