ID   SDR1_PICAB              Reviewed;         271 AA.
AC   Q08632;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Short-chain type dehydrogenase/reductase;
DE            EC=1.-.-.-;
OS   Picea abies (Norway spruce) (Picea excelsa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX   NCBI_TaxID=3329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8290650; DOI=10.1104/pp.103.4.1479;
RA   Bauer S., Galliano H., Pfeiffer F., Messner B., Sandermann H. Jr.,
RA   Ernst D.;
RT   "Isolation and characterization of a cDNA clone encoding a novel short-
RT   chain alcohol dehydrogenase from Norway spruce (Picea abies L. Karst).";
RL   Plant Physiol. 103:1479-1480(1993).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X74115; CAA52213.1; -; mRNA.
DR   PIR; S34678; S34678.
DR   AlphaFoldDB; Q08632; -.
DR   SMR; Q08632; -.
DR   PRIDE; Q08632; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   2: Evidence at transcript level;
KW   Oxidoreductase.
FT   CHAIN           1..271
FT                   /note="Short-chain type dehydrogenase/reductase"
FT                   /id="PRO_0000054774"
FT   ACT_SITE        179
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         25..49
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         166
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   271 AA;  28725 MW;  743EA1CBB2F85FE3 CRC64;
     MATADEQEEE MRMRLPLPLG GRVAIVTGAS RGIGREIALN MAEKGAKVVI HYSSNQHAAE
     EVASIINNKS PSSGDGVRAI VCKADVAEPS QVAQLFDTAE HAFGPLHIVV NNAGVTDSKY
     PTLAQTSDEE WDRIFQVNCK GAFLCSREAA KRVVRGGGGR IINISSSLVA MPIPRYGAYT
     ASKAAVEMMT RILAQELRGT QITANCVAPG PVATDMFFAG KSEAAVEAGV KSNPFERLGK
     VEDVAPLVAF LASDEGEWVN AQVVRVNGGQ V