SDR3B_ARATH
ID SDR3B_ARATH Reviewed; 257 AA.
AC Q94K41; O80712;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Short-chain dehydrogenase reductase 3b;
DE Short=AtSDR3b;
DE EC=1.1.1.-;
GN Name=SDR3b; Synonyms=SDR3, SDR5; OrderedLocusNames=At2g47140;
GN ORFNames=F14M4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
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DR EMBL; AC004411; AAC34234.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC10806.1; -; Genomic_DNA.
DR EMBL; AF370319; AAK44134.1; -; mRNA.
DR EMBL; AY063106; AAL34280.1; -; mRNA.
DR PIR; T02174; T02174.
DR RefSeq; NP_566097.1; NM_130282.2.
DR AlphaFoldDB; Q94K41; -.
DR SMR; Q94K41; -.
DR STRING; 3702.AT2G47140.1; -.
DR PaxDb; Q94K41; -.
DR PRIDE; Q94K41; -.
DR ProteomicsDB; 232954; -.
DR EnsemblPlants; AT2G47140.1; AT2G47140.1; AT2G47140.
DR GeneID; 819327; -.
DR Gramene; AT2G47140.1; AT2G47140.1; AT2G47140.
DR KEGG; ath:AT2G47140; -.
DR Araport; AT2G47140; -.
DR TAIR; locus:2041394; AT2G47140.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_0_1; -.
DR OMA; FSSISYM; -.
DR OrthoDB; 913128at2759; -.
DR PhylomeDB; Q94K41; -.
DR BioCyc; ARA:AT2G47140-MON; -.
DR PRO; PR:Q94K41; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q94K41; baseline and differential.
DR Genevisible; Q94K41; AT.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 2: Evidence at transcript level;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..257
FT /note="Short-chain dehydrogenase reductase 3b"
FT /id="PRO_0000419512"
FT ACT_SITE 157
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 12..36
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
FT BINDING 144
FT /ligand="substrate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 257 AA; 26847 MW; 4015B27D6C6A8830 CRC64;
MSGKRLDGKI VIITGGASGI GAESVRLFTE HGARVVIVDV QDELGQNVAV SIGEDKASYY
HCDVTNETEV ENAVKFTVEK YGKLDVLFSN AGVIEPFVSI LDLNLNELDR TIAINLRGTA
AFIKHAARAM VEKGIRGSIV CTTSVAAEIA GTAPHGYTTS KHGLLGLIKS ASGGLGKYGI
RVNGVAPFGV ATPLVCNGFK MEPNVVEQNT SASANLKGIV LKARHVAEAA LFLASDESAY
VSGQNLAVDG GYSVVKP