SDR3C_ARATH
ID SDR3C_ARATH Reviewed; 258 AA.
AC O80714;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Short-chain dehydrogenase reductase 3c;
DE Short=AtSDR3c;
DE EC=1.1.1.-;
GN Name=SDR3c; OrderedLocusNames=At2g47120; ORFNames=F14M4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
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DR EMBL; AC004411; AAC34218.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10804.1; -; Genomic_DNA.
DR PIR; T02176; T02176.
DR RefSeq; NP_182234.1; NM_130280.1.
DR AlphaFoldDB; O80714; -.
DR SMR; O80714; -.
DR STRING; 3702.AT2G47120.1; -.
DR PaxDb; O80714; -.
DR EnsemblPlants; AT2G47120.1; AT2G47120.1; AT2G47120.
DR GeneID; 819325; -.
DR Gramene; AT2G47120.1; AT2G47120.1; AT2G47120.
DR KEGG; ath:AT2G47120; -.
DR Araport; AT2G47120; -.
DR TAIR; locus:2041449; AT2G47120.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_0_1; -.
DR InParanoid; O80714; -.
DR PhylomeDB; O80714; -.
DR PRO; PR:O80714; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80714; baseline and differential.
DR Genevisible; O80714; AT.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..258
FT /note="Short-chain dehydrogenase reductase 3c"
FT /id="PRO_0000419513"
FT ACT_SITE 156
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 12..36
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
FT BINDING 144
FT /ligand="substrate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 258 AA; 27259 MW; 0417B5E23F5B1E90 CRC64;
MSGLRLEGKI VIITGGASGI GADAARLFTD HGAKVVIVDV QEELGQNVAV LIGKDKASFY
RCDVTNETEV EDAVKFTVEK HGKLDVLFSN AGVLEPLESF LDFDLERFDR IMAVNVRGAA
AFIKHAARAM VEKGTRGSIV CTTSVSAEIG GGHHGYTASK HGLVGLIRSA CGDLGKYGIR
VNGVAPYAVA TPMTSHDEVT GKQLEDYFDA KGILKGMVLK ASHVAQVALF LASDDSAYIS
GQNLAVDGGY TVVKPSRD
