SDR5_ARATH
ID SDR5_ARATH Reviewed; 259 AA.
AC F4J300; Q9LS67;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Short-chain dehydrogenase reductase 5;
DE Short=AtSDR5;
DE EC=1.1.1.-;
GN Name=SDR5; OrderedLocusNames=At3g29260; ORFNames=MXO21.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12417697; DOI=10.1105/tpc.006494;
RA Cheng W.-H., Endo A., Zhou L., Penney J., Chen H.-C., Arroyo A., Leon P.,
RA Nambara E., Asami T., Seo M., Koshiba T., Sheen J.;
RT "A unique short-chain dehydrogenase/reductase in Arabidopsis glucose
RT signaling and abscisic acid biosynthesis and functions.";
RL Plant Cell 14:2723-2743(2002).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01824.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB026657; BAB01824.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77559.1; -; Genomic_DNA.
DR RefSeq; NP_189571.1; NM_113850.1.
DR AlphaFoldDB; F4J300; -.
DR SMR; F4J300; -.
DR STRING; 3702.AT3G29260.1; -.
DR PaxDb; F4J300; -.
DR PRIDE; F4J300; -.
DR ProteomicsDB; 232670; -.
DR EnsemblPlants; AT3G29260.1; AT3G29260.1; AT3G29260.
DR GeneID; 822582; -.
DR Gramene; AT3G29260.1; AT3G29260.1; AT3G29260.
DR KEGG; ath:AT3G29260; -.
DR Araport; AT3G29260; -.
DR TAIR; locus:2094822; AT3G29260.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_0_1; -.
DR InParanoid; F4J300; -.
DR OMA; VWDTTMA; -.
DR OrthoDB; 1373099at2759; -.
DR PRO; PR:F4J300; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; F4J300; baseline and differential.
DR Genevisible; F4J300; AT.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..259
FT /note="Short-chain dehydrogenase reductase 5"
FT /id="PRO_0000419515"
FT ACT_SITE 157
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 12..36
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
FT BINDING 144
FT /ligand="substrate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 259 AA; 26925 MW; D9162979672A9542 CRC64;
MSGQRLDGKI VIITGGASGI GAEAARLFTD HGAKVVIVDL QEELGQNVAV SIGLDKASFY
RCDITDETEV ENAVKFTVEK HGKLDVLFSN AGVMEPHGSI LDLDLEAFDR TMAVNVRGAA
AFIKHAARSM VASGTRGSIV CTTSVTAEIG GPGPHSYTAS KHALLGLVRS ACGGLGKYGI
RVNGVAPYGV ATGLTSYNEE TVKMVEDYCS ATAILKGVVL KARHVADAAL FLASDDSVYI
SGQNLGVDGG YSVVKLTSN
